Dermatology Practical & Conceptual

Regression of nevi in a melanoma patient treated with interferon

…ritic cells (Figure 4). These dendritic cells could represent melanocytes, raising the possibility of pagetoid spread of a melanoma or Langerhans cell, as part of the inflammation. Histopathologic analysis of this lesion showed a dysplastic nevus wit…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

-oid?

…nocytic nevus, so-called nevus cells that really are abnormal melanocytes. If the word nevus is abstruse, then nevoid (or nevic) is opaque. And what of the words “mucoid” and “myxoid,” as in the cyst that lacks a lining of epi…

Dermatology Practical & Conceptual

When all you have is a dermatoscope—start looking at the nails

…eatening diseases are possible underlying causes. Nail matrix melanocytes of unaffected individuals are in a dormant state, and, therefore, fingernails and toenails physiologically are non-pigmented. The formation of continuous, longitudinal pigmente…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Perivascular Dermatitis

….36 A&B), the so-called nevus cells really being abnormal melanocytes. Figure 5.35 A&B. Simulation of an inflammatory disease. A perivascular lymphoplasmacytic infiltrate, such as this, could be misconstrued as that of a dermatitis, e.g.,…

Histologic Diagnosis of Inflammatory Skin Diseases

Tinea nigra

…the cornified layer of benign and malignant proliferations of melanocytes. Stain of skin by silver nitrate has an unnatural appearance because it is caused artifactually. It can be scraped off because the discoloration resides in the outer part of th…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Borderline, Minimal Deviation, and Nevoid Melanomas?

…iation melanoma have been described . . . A small nodule of melanocytes that show moderate to moderately severe atypism and impinge on the reticular dermis . . . Minimal deviation melanomas that share some histologic features with a Spitz tumor. Ha…