Differential Diagnosis in Dermatopathology

Discussions

Apocrine and eccrine hidradenomas have numerous findings histopathologic in common. Their silhouette is that of a benign neoplasm, characterized as it is by symmetry, sharp circumscription, smooth borders, compressed fibrous tissue at the peripherie…

Dermatology Practical & Conceptual

Lecture Series

The free Adobe Flash Player is required to view these videos. Lecture Series: A series of lectures by A. Bernard Ackerman, MD on subjects from A Clinical Atlas of 101 Common Skin Diseases. Read Introduction A series of lectures by A. Bernard Acker…

Differential Diagnosis in Dermatopathology

Discussions

Syringocystadenoma papilliferum and hidradenoma papilliferum are both apocrine papillated cystadenomas. Clinically, syringocystadenoma papilliferum appears at birth or in early childhood as a crusted, often weeping, verrucous plaque, usually on the…

Differential Diagnosis in Dermatopathology

Metastatic carcinoma from a breast vs. Morpheiform basal-cell carcinoma

A hamartoma of epidermis, epithelial structures of adnexa, and presumably dermal elements, typified, when fully formed, by a papillated or verrucous yellowish plaque situated usually on the scalp. The condition may present itself as a solitary lesio…

Differential Diagnosis in Dermatopathology

Discussions

The neoplasms under discussion here are termed “mixed tumors” because they consist of a combination of epithelial elements with tubular differentiation on one hand and non-epithelial elements with mucinous and chondroid aspects, but they…

Differential Diagnosis in Dermatopathology

Discussions

The most important finding that granular-cell tumors and xanthomas have in common is diffuse dermal infiltrates of monomorphous cells that possess abundant pale-staining cytoplasm. The cytoplasm may have either a basophilic or eosinophilic hue in se…

Differential Diagnosis in Dermatopathology

Apocrine (clear-cell) hidradenoma vs. Eccrine (poroid) hidradenoma

A hamartoma of epidermis, epithelial structures of adnexa, and presumably dermal elements, typified, when fully formed, by a papillated or verrucous yellowish plaque situated usually on the scalp. The condition may present itself as a solitary lesio…

Differential Diagnosis in Dermatopathology

Granular-cell tumor vs. Xanthoma

A hamartoma of epidermis, epithelial structures of adnexa, and presumably dermal elements, typified, when fully formed, by a papillated or verrucous yellowish plaque situated usually on the scalp. The condition may present itself as a solitary lesio…