Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ingly abnormal lymphocytes in the dermis = Mycosis fungoides, nodule  The ulcer is a consequence of the effects of the lymphomatous process, rather than of external trauma. Abnormal lymphocytes are present in the acanthotic epidermis, as well as in t…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

-oid?

…alisade, as is the case for granuloma annulare and rheumatoid nodule. “Histiocytes,” as the neoplastic cells of epithelial sarcoma are claimed to be, are nonepithelial and, therefore, referring to them as “epithelioid is, at the lea…

Dermatology Practical & Conceptual

Pigmented tumor in the nostril

…melanin [5]. The lesion most often arises as a solitary skin nodule on the face (85%) [4]; however, multiple IFK have been described in Cowden’s syndrome [6]. The cheek and the upper lip are the sites of predilection; other sites affected are…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Reactive Perforating Collagenosis?

…case for chondrodermatitis nodularis helices, picker’s nodules, surfer’s nodules, and nodules that form at the base of an amputation stump; the trauma in those conditions, however, results from something other than scratching. In short,…

Differential Diagnosis in Dermatopathology

Discussions

…theme pathologic. Clinically, xanthogranulomas are papules or nodules with a yellow, orange, or tan cast. The color results from abundant lipid in the cytoplasm of histiocytes that constitute the bulk of the lesion. The condition is better termed xan…

Dermatology Practical & Conceptual

Incidental Merkel cell carcinoma in a cutaneous horn: a case report

…ch usually presents as an asymptomatic, rapidly growing, firm nodule on sun-damaged skin. We present a 93-year-old female who presented with a “cutaneous horn” on the face. On excision, histologic examination revealed a combined squamous cell carcino…

Dermatology Practical & Conceptual

The dermatoscopic universe of basal cell carcinoma

…essels and blue-gray ovoid nests (a). Although nor the second nodule displays a pigment network, it exhibits dotted vessels and its pigmented structures are irregular brown/black globules and irregular peripheral streaks, in contrast to the well-circ…