Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.22.1A: Vesicular dermatitis, intraepidermal, spongiotic + 10.22.1B: Hyphae in the cornified layer = Dermatophytosis Were there no hyphae present in the stratum corneum, the differential diagnosis also would include allergic cont…

Differential Diagnosis in Dermatopathology

Discussions

…ngiosis are other indications of the dynamic nature of guttate psoriasis. Guttate parapsoriasis is much more indolent than guttate psoriasis. In sections of tissue from biopsy specimens taken sequentially very slight spongiosis is evident in sections…

Histologic Diagnosis of Inflammatory Skin Diseases

Pellagra

Pellagra Synonyms Niacin deficiency Presentation stereotypical Age and sex Any age and either sex; more common in developing countries in which malnutrition is prevalent, but may be seen in industrialized countries where factors for malnutrition, e….

Dermatology Practical & Conceptual

Microscopic examination of normal nail clippings

…ifferences in nail clippings between dystrophic changes due to psoriasis and onychomycosis, compared to normal controls. They examined four cases of onychomycosis, 14 cases of psoriasis and five normal controls. In nails with psoriasis they concluded…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…f the epidermis and papillary dermis resembles closely that of psoriasis, but the combination of lichenoid infiltration and numerous lymphocytes in the epidermis militates against psoriasis and indicates mycosis fungoides. 11.14.3A: Nodular der…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…y by neutrophils in foci of parakeratosis. Eruptive lesions of psoriasis (guttate psoriasis) also display neutrophils in mounds of parakeratosis, but at no stage is psoriasis an interface dermatitis. 10.66.7A: Perivascular dermatitis, interface…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Psychocutaneous Disorders?

“The influence of the psyche on the skin is greater than on any other organ. It is apparent in the many cutaneous expressions of the emotions, subjective, as well as objective, both in man and in animals. It is for this reason that the skin i…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Necrotizing Vasculitis?

…nson does not communicate that that disease really is pustular psoriasis and the appellation necrotizing vasculitis does not convey the idea that the condition is leukocytoclastic vasculitis. One name for a disease is enough; pustular psoriasis and l…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Figurate Erythemas?

“Erythema in Patches and Figured Erythema—These consist of congestive spots, patches, or surfaces of irregular shape, discoidal or of variable configuration (erythema marginatum or annulare, etc.). Although sometimes infectious, this t…