Search Results for: seckel\\'s syndrome

Differential Diagnosis in Dermatopathology

Pemphigus vulgaris vs. Grover’s disease, pemphigus vulgaris-like

Lupus erythematosus (LE) is a multisystem autoimmune connective tissue disease that can have protean effects on the skin. In some patients only the skin is involved, while in others, life-threatening internal complications can arise, ranging from…

Histologic Diagnosis of Inflammatory Skin Diseases

Miescher’s granuloma of the face

…fter many months Differential diagnosis clinical Sarcoidosis, especially in African-Americans, consists of papules that may assume annular configuration, but they favor sites around the eyes, nose, and mouth. Tinea faciei may display scales at the…

Histologic Diagnosis of Inflammatory Skin Diseases

Grover’s disease

…40 years and usually over age 60 years; white men mostly Distribution of lesions Widespread, but especially the trunk and less often the proximal part of the extremities Arrangement of lesions Scattered and discrete; sometimes so numerous as to be…

Differential Diagnosis in Dermatopathology

Dermatofibroma vs. Desmoplastic Spitz’s nevus

Lupus erythematosus (LE) is a multisystem autoimmune connective tissue disease that can have protean effects on the skin. In some patients only the skin is involved, while in others, life-threatening internal complications can arise, ranging from…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Mammary and Extramammary Paget’s Disease?

…ialr clincial features that mimic inflammatory or infectous conditions. Whereas mammary Paget’s disease is most often assoicated with an underlying carcinima of the breast, extramammary Paget’s disease is a heterogenous condition…

Differential Diagnosis in Dermatopathology

Spitz’s nevus, compound type vs. Melanoma

Lupus erythematosus (LE) is a multisystem autoimmune connective tissue disease that can have protean effects on the skin. In some patients only the skin is involved, while in others, life-threatening internal complications can arise, ranging from…

Histologic Diagnosis of Inflammatory Skin Diseases

Kimura’s disease

…and tumors, some gigantic, above which the skin appears normal Course Protracted Findings histopathologic Fully developed Massive nodular and diffuse infiltrate of lymphocytes and eosinophils throughout the reticular dermis and subcutaneous tissue…

Histologic Diagnosis of Inflammatory Skin Diseases

Crohn’s disease

Lupus erythematosus (LE) is a multisystem autoimmune connective tissue disease that can have protean effects on the skin. In some patients only the skin is involved, while in others, life-threatening internal complications can arise, ranging from…

Development of poorly differentiated invasive squamous cell carcinoma in giant Bowen’s disease: a case report with dermatoscopy

Development of poorly differentiated invasive squamous cell carcinoma in giant Bowen’s disease: a case report with dermatoscopy

…rm of squamous cell carcinoma (SCC), often occurring in the chronically UV-damaged skin of elderly people. The risk of progression of BD to invasive SCC varies between 3% and 5%, and one-third of invasive tumors may metastasize. Herein we discuss