Search Results for: x-linked ichthyosis

Dermatology Practical & Conceptual

Yellow color upon dermatoscopy does not exclude melanoma!

…k, bright red, purple or blue. Instead, yellow color has been linked to keratin or lipids, and accordingly, it is commonly seen in keratinizing tumors including seborrheic keratosis and squamous cell carcinoma or in tumors with sebaceous differentiat…

Histologic Diagnosis of Inflammatory Skin Diseases

Incontinentia pigmenti

…Laboratory confirmation Genetic mapping for mutations in the Xp I I.21 or the Xq28 locus. Cause and mechanism This hereditary systemic disease is caused by an Xlinked genetic defect in loci Xp I I.21 or Xq28, which is dominant in females and usuall…

Histologic Diagnosis of Inflammatory Skin Diseases

Lupus erythematosus

…nyms Lupus erythematodes Presentation stereotypical Age and sex Young adult women especially, but sometimes neonates and older persons of both sexes. Distribution of lesions Often localized to sun-exposed sites such as the face, chest, and arms, but…

Differential Diagnosis in Dermatopathology

Discussions

…t is situated entirely or mostly in the subcutaneous fat. No expression of granuloma annulare, however, is linked to arthritis. The cause of granuloma annulare is unknown, but the condition has been reputed to follow insults of many kinds, among them…

Histologic Diagnosis of Inflammatory Skin Diseases

Acrodermatitis chronica atrophicans

…tis chronica atrophicans Presentation stereotypical Age and sex Middle aged to elderly women especially Distribution of lesions Distal part of extremities, particularly of legs; nodules develop especially near knees and elbows Configuration of lesion…

Dermatology Practical & Conceptual

Epidermal multinucleated giant cells are not always a histopathologic clue to a herpes virus infection: multinucleated epithelial giant cells in the epidermis of lesional skin biopsies from patients with acantholytic dermatoses can histologically mimic a herpes virus infection

…toses in which herpes virus infection has been observed to coexist. Methods: Two individuals with acantholytic dermatoses whose initial lesional skin biopsies showed multinucleated epithelial giant cells suggestive of a herpes virus infection are rep…

Histologic Diagnosis of Inflammatory Skin Diseases

Pemphigus foliaceus

Pemphigus foliaceus Presentation stereotypical Age and sex Adults usually and of both sexes Distribution of lesions Localized to photodistribution in pemphigus erythematosus; widespread in pemphigus foliaceus Individual lesions Macules, patches, fla…