Search Results for: x-linked ichthyosis

Histologic Diagnosis of Inflammatory Skin Diseases

Incontinentia pigmenti

…pping for mutations in the Xp I I.21 or the Xq28 locus. Cause and mechanism This hereditary systemic disease is caused by an Xlinked genetic defect in loci Xp I I.21 or Xq28, which is dominant in females and usually lethal in males. The mechanism…

Diagnostic utility of Ki-67 and Cyclin D1 immunostaining in differentiation of psoriasis vs. other psoriasiform dermatitis

Diagnostic utility of Ki-67 and Cyclin D1 immunostaining in differentiation of psoriasis vs. other psoriasiform dermatitis

…e adjacent to the MMP-19 positive cells, mainly in the rete ridges, and was thought to be associated with remodeling of the extracellular matrix during inflammation [24]. The majority of T cells in established psoriatic plaques express cell-surface…

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Histologic Diagnosis of Inflammatory Skin Diseases

Lupus erythematosus

…odes Presentation stereotypical Age and sex Young adult women especially, but sometimes neonates and older persons of both sexes. Distribution of lesions Often localized to sun-exposed sites such as the face, chest, and arms, but may be widespread,…

Histologic Diagnosis of Inflammatory Skin Diseases

Pemphigus foliaceus

…lococcal scalded skin syndrome. Both bullous impetigo and staphylococcal scalded skin syndrome are caused by staphylococcal exotoxins, namely, exfoliatin released from bacteria in the blister in the case of bullous impetigo and exfoliatin released…

Differential Diagnosis in Dermatopathology

Discussions

…is no predilection for sex. Clinically, skin lesions often are cord-like bands, especially on the trunk, but also on the proximal part of upper extremities. Arthritis may precede the development of skin lesions of interstitial granulomatous…