Histologic Diagnosis of Inflammatory Skin Diseases

Acrodermatitis chronica atrophicans

Acrodermatitis chronica atrophicans Presentation stereotypical Age and sex Middle aged to elderly women especially Distribution of lesions Distal part of extremities, particularly of legs; nodules develop especially near knees and elbows Configurati…

Dermatology Practical & Conceptual

Epidermal multinucleated giant cells are not always a histopathologic clue to a herpes virus infection: multinucleated epithelial giant cells in the epidermis of lesional skin biopsies from patients with acantholytic dermatoses can histologically mimic a herpes virus infection

Abstract Background: Multinucleated giant cells in the epidermis can either be epithelial or histiocytic. Epithelial multinucleated giant cells are most often associated with herpes virus infections. Purpose: To review the histologic differential di…

Differential Diagnosis in Dermatopathology

Discussions

Nodular vasculitis and subcutaneous polyarteritis nodosa are inflammatory diseases that affect medium-sized and large arteries situated in fibrous septa of the subcutaneous fat. Both conditions involve the subcutaneous fat mostly, although signs of…