Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Benign and Malignant Cells?

st is the recognition that cells of a benign neoplasm may have startlingly large and pleomorphic nuclei, e.g., those of some Spitz nevi and of ancient Miescher’s nevi, and in reverse, cells of some malignant neoplasms may display remarkably sma…

Differential Diagnosis in Dermatopathology

Discussions

…ck-bite granuloma), of melanomas (e.g., persistent melanocytic nevi following partial surgical removal; Spitz’s nevi; ancient nevi; and melanocytic nevi on special sites, such as the breast (especially nipple and areola), genitalia, perianal re…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Epidemic of Melanoma?

…149:43-46. “The epidemic of melanoma poses problems for several constituencies.” Clark WH, Elder DE, Guerry IV D. Dysplastic nevi and malignant melanoma. In: Farmer ER, Hood AF, eds. pathology of the skin. Norwalk, CT: Appleton & La…

Dermatology Practical & Conceptual

The order of things and the classification of melanoma

…a it is highly complex and diverse in its forms of appearance. Scientists attempt to bring order to the diversity of biologic phenomena by defining groups on the basis of shared characteristics and by giving names to these groups. What we call knowle…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Ichthyoses?

…f clinical, histological, and cellular kinetic observations, a separation of the major ichthyosiform dermatoses into four groups is proposed. Ichthyosis vulgaris patients have dry skin and fine scales on their trunk and extremities, but gross changes

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Radial Growth Phase versus Vertical Growth Phase of Melanoma?

…lasm that has not been previously manifested in the neoplastic system.” Clark WH Jr, Elder DE, Guerry IV D, et al. Dysplastic nevi and malignant melanoma. In: Farmer ER, Hood AF, eds. Pathology of the Skin. Norwalk, CT: Appleton & Lange, 1…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Sebaceous Epithelioma?

…erentiation or sebaceous epithelioma. These tumors are usually solitary, yellowish papulonodules on the face or scalp, but they are sometimes multiple, particularly in Muir-Torre syndrome, or associated with organoid nevi.” Weedon D. Skin Path…