Search Results for: fibrin

Histologic Diagnosis of Inflammatory Skin Diseases

Limitations of the Algorithmic Method

…utrophilic vasculitis” in which many vessels in a particular section of tissue show signs of vasculitis in the form of fibrin in the wall of venules or thrombi in the lumen of them, never is that the case for “lymphocytic…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…ften preserved 5. Neutrophils in collections, nuclear “dust of neutrophils,” basophilia of collagen bundles, and fibrin at the tip of dermal papillae are present beneath and at the sides of a blister 5. No neutrophils, basophilia of…

Histologic Diagnosis of Inflammatory Skin Diseases

Leprosy

…nt of nerve fascicles by granulomas (a consequence of neurotropism by leprae bacilli), and absence of caseous necrosis or of fibrin in the center of granulomas. In brief, a histopathologist may offer a diagnosis presumptive of tuberculoid leprosy,…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…“bites” of insects and of mites of scabies, sometimes induce changes of small-vessel vasculitis as manifested by fibrin in the wall of venules, as shown here, thrombi in lumen of venules, or both of them together. 10.5.9A: Vesicular…

From the Dermatologikum Hamburg

From the Dermatologikum Hamburg

…he dermis and are dominated by far by neutrophils. Some nuclear dust of neutrophils is present but there is no deposition of fibrin in the vessel walls. Fibrosis is seen in the deeper dermis. In the absence of clinical information, the best…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Necrotizing Vasculitis?

…nvolved cannot be necrotic because collagen is a nonviable fiber. In lesions of leukocytoclastic vasculitis developed fully, fibrin is present in the wall of venules, but those vessels themselves are not necrotic. Of course, occlusion of lumina in…

Differential Diagnosis in Dermatopathology

Lupus erythematosus profundus vs. Panniculitis-like T-cell lymphoma

A type of small-vessel vasculitis (venulitis) of the skin, occurring especially in the vicinity of the ankle, characterized at first by purpuric macules and patches that, in time, may become hemorrhagic blisters that ulcerate and heal with white,…

Differential Diagnosis in Dermatopathology

Herpes simplex vs. Vaccinia

A type of small-vessel vasculitis (venulitis) of the skin, occurring especially in the vicinity of the ankle, characterized at first by purpuric macules and patches that, in time, may become hemorrhagic blisters that ulcerate and heal with white,…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…fat and degenerated collagen sometimes 10. No calcification in the reticular dermis or the subcutaneous fat 11. Deposits of fibrin at the periphery of fat lobules 11. No deposits of fibrin at the periphery of lobules 12. Findings diagnostic of…

Histologic Diagnosis of Inflammatory Skin Diseases

Precepts Adjunctive to the Algorithmic Method

…; re-epithelialization beneath a subepidermal blister because it represents an anticipated physiologic response; deposits of fibrin beneath erosions and ulcerations because they are a consequence inevitably of whatever injury was responsible for…