Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.67.1A: Panniculitis, septal mostly + 10.67.1B: Histiocytes in palisaded array around large foci of degenerated collagen in the reticular dermis + 10.67.1C + 10.67.1D = Necrobiosis lipoidica¬†Vasculitis, as can be see…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

-oid?

“-oid (-oid) [eides, like]. A suffix signifying likeness or resemblance.” Bould G. The Practitioner’s Medical Dictionary. 3rd ed. Philadelphia, PA: P. Blakiston’s Son & Co., 1916:622. “-ode, -odes, -oid, -oides […

Histologic Diagnosis of Inflammatory Skin Diseases

Erythema elevatum diutinum

Erythema elevatum diutinum Presentation stereotypical Age and sex Any age, but usually young adults, women especially Distribution of lesions Symmetrical over joints especially, particularly the dorsa of the hands and the elbows and knees Shape of l…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.52.1A: Perivascular and interstitial dermatitis + 10.52.1B: Lymphocytes, plasma cells, neutrophils, and eosinophils in company with fibrocytes and histiocytes, the latter being predominant = Interstitial granulomatous dermatitis…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Dermatofibroma?

“Cutaneous fibroma Fibroma simplex Simple fibroma of the skin, as defined above, is a benign tumor, usually appearing solitary, on the upper part of the body and the extremities, which, mainly imbedded in the skin, is only rarely and little…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.33.1A: Panniculitis, mostly septal + 10.33.1B: Neutrophils among tiny collections of histiocytes and clefts within those collections = Erythema nodosum These findings represent an early stage in the evolution of erythema nodosum…

Differential Diagnosis in Dermatopathology

Discussions

Early changes in papulonodular lesions of dermatofibromas are similar, in many respects, to those in Kaposi’s sarcoma. Both are dome-shaped and consist of proliferations that are highly cellular. Most of the cells are oval and they are joined…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…nomaly elongate) 2. Collagen bundles arranged haphazardly 3. Fibrocytes normal cytologically not usually increased in number 3. Fibrocytes often large, stellate, or multinucleate are markedly increased in number 4. Collagen bundles thick and coa…