Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Dysplasia?

…;atypical melanocytic hyperplasia” in the epidermis and fibroplasias, sparse lymphocytic infiltrates, and telangiectases in the papillary dermis. Clark and his group had come to view the shoulders of these nevi as abnormal because they had been…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ance obtains, it fails to qualify as an inflammatory disease. Fibroplasia immediately beneath blisters is a sequela invariable. 10.28.2A: Vesicular dermatitis, subepidermal, mixed-cell + 10.28.2B: Slight fibrosis in the upper part of the de…

Histologic Diagnosis of Inflammatory Skin Diseases

Acquired epidermolysis bullosa

…low the lamina densa. A scar observed clinically is marked by fibroplasia in the upper part of the dermis. Milia are tiny infundibular cysts that form in the process of re-epithelization beneath blisters. Differential diagnosis histopathologic Derma…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…12. Mucin in the stroma sometimes 12. No mucin 13. Diffuse fibroplasia 13. Fibroplasia around lobules of endothelial cells at the periphery of a lesion 14. Thickened bundles of collagen within the lesion itself, especially at the periphery of it…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…inucleate, in company with numerous lymphocytes and incipient fibroplasia in a widened fibrous septum + 10.33.5C + 10.33.5D = Erythema nodosumĀ At scanning magnification, the pattern formed by infiltrates of inflammatory cells is diagnost…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Metastasizing Dermatofibroma?

…ecome flat or even delled, a consequence of retraction of the fibroplasia. All of the attributes just chronicled are indicative of an inflammatory process. During the stage in development of dermatofibroma in which histiocytes predominate (referred t…

Histologic Diagnosis of Inflammatory Skin Diseases

Incontinentia pigmenti

…elanophages in the papillary dermis Atrophic lesions Slight fibroplasia in the upper part of the dermis Loss of the undulate pattern between dermal papillae and epidermal rete ridges; base of the epidermis flat Melanophages in the papillary dermis…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Sclerotic Fibroma?

…fibroma is neither a hamartoma nor a benign neoplasm. It is a fibroplasia, i.e., a type of fibrosis, in which at first there is an increase in number of fibrocytes in conjunction with ribbons of collagen arranged in fascicles that interweave. That di…