Search Results for: hypergranulosis

Histologic Diagnosis of Inflammatory Skin Diseases

Lichen striatus

…the upper part of the dermis. Differential diagnosis histopathologic Lichen planus displays compact orthokeratosis, V-shaped hypergranulosis, and jagged acanthosis; only in lichen planopilaris are infiltrates of lymphocytes distributed along the…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…Individual necrotic cells often within lobules of isthmic epithelium 10. No signs of lichen simplex chronicus usually 10. Signs of lichen simplex chronicus in the form of compact orthokeratosis and hypergranulosis often…

Differential Diagnosis in Dermatopathology

Allergic contact dermatitis vs. Irritant contact dermatitis

Loss of hair attributable either to the effects of inflammatory cells on follicles or to physiological or mechanical factors in which inflammatory cells play no role. Although the scalp is the site most often affected, any region of the skin that…

Differential Diagnosis in Dermatopathology

Discussions

…act orthokeratosis, an epidermis thinned focally, a pattern of rete ridges and dermal papillae that is muted markedly, focal hypergranulosis, necrotic keratocytes at the dermoepidermal junction and in the uppermost dermis, vacuolar alteration at the…

Differential Diagnosis in Dermatopathology

Dilated pore vs. Pilar sheath acanthoma

Loss of hair attributable either to the effects of inflammatory cells on follicles or to physiological or mechanical factors in which inflammatory cells play no role. Although the scalp is the site most often affected, any region of the skin that…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…Leukokeratosis Leukoplakia 1. Orthokeratosis with few parakeratotic cells 1. Parakeratosis with few orthokeratotic cells 2. Hypergranulosis 2. Few, if any, granular cells in a lesion that has not been rubbed persistently 3. Epithelium thickened…

Diagnostic utility of Ki-67 and Cyclin D1 immunostaining in differentiation of psoriasis vs. other psoriasiform dermatitis

Diagnostic utility of Ki-67 and Cyclin D1 immunostaining in differentiation of psoriasis vs. other psoriasiform dermatitis

…dermal papillae [1]. The presence of thickened collagen bundles arranged in vertical streaks in the dermal papillae, marked hypergranulosis and a thick layer of compact orthokeratosis resembling that seen on normal palms and soles (i.e., hairy palm…

Pigmented Lesions

Pigmented Lesions

…orm, plasmacytoid, and polygonal. Pseudoacantholysis of melanocytes is common. Often there are compact orthokeratosis, focal hypergranulosis, adnexal hyperplasia, dull pink globules in the epidermis, and clefts between nests/fascicles of melanocytes…