Differential Diagnosis in Dermatopathology

Nevus verrucosus vs. Acanthosis nigricans

Papules on skin and mucous membranes that result from infection of keratinocytes by different types of papillomavirus and classified according to their silhouettes, to wit, papillated (verrucae vulgares on different sites such as volar skin, i.e., v…

Differential Diagnosis in Dermatopathology

Alopecia areata vs. Trichotillomania

Papules on skin and mucous membranes that result from infection of keratinocytes by different types of papillomavirus and classified according to their silhouettes, to wit, papillated (verrucae vulgares on different sites such as volar skin, i.e., v…

Differential Diagnosis in Dermatopathology

Keratoacanthomatous verruca vulgaris vs. Verrucous keratoacanthoma

Papules on skin and mucous membranes that result from infection of keratinocytes by different types of papillomavirus and classified according to their silhouettes, to wit, papillated (verrucae vulgares on different sites such as volar skin, i.e., v…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Leukokeratosis Leukoplakia 1. Orthokeratosis with few parakeratotic cells 1. Parakeratosis with few orthokeratotic cells 2. Hypergranulosis 2. Few, if any, granular cells in a lesion that has not been rubbed persistently 3. Epithelium thicke…

Differential Diagnosis in Dermatopathology

Discussions

Leukokeratosis and leukoplakia are white, slightly elevated nonindurated lesions of the mucosae (especially of the mouth, but also of the vagina and other areas) that also have some attributes histopathologic in common, namely, hyperkeratosis, a thi…

Differential Diagnosis in Dermatopathology

Dilated pore vs. Pilar sheath acanthoma

Papules on skin and mucous membranes that result from infection of keratinocytes by different types of papillomavirus and classified according to their silhouettes, to wit, papillated (verrucae vulgares on different sites such as volar skin, i.e., v…

Differential Diagnosis in Dermatopathology

Pigmented Lesions

Non-melanocytic lesions Inflammatory Post-inflammatory hyperpigmentation¬†(523, 649) Melanophages in number variable scattered in the papillary dermis, rarely in the upper part of the reticular dermis too. Melanin increased in amount in the epi…

Differential Diagnosis in Dermatopathology

Discussions

Epidermolytic hyperkeratosis and a plane wart share several findings histopathologic, among them being a papillated and thickened epidermis, hypergranulosis, and cells with pale cytoplasm within the epidermis. The terms “epidermolytic hyperker…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Nevus verrucosus Acanthosis nigricans 1. Orthokeratosis compact 1. Orthokeratosis in basket-woven and lamellate patterns 2. Thick epidermis, either papillated or digitated 2. Thin epidermis 3. Hypergranulosis usually 3. Granular zone normal…