Differential Diagnosis in Dermatopathology

Epidermolytic hyperkeratosis vs. Plane wart

Papules on skin and mucous membranes that result from infection of keratinocytes by different types of papillomavirus and classified according to their silhouettes, to wit, papillated (verrucae vulgares on different sites such as volar skin, i.e., v…

Differential Diagnosis in Dermatopathology

Discussions

…d in vertical streaks and of compact orthokeratosis joined by hypergranulosis. The differential diagnosis histopathologic of allergic contact dermatitis at all stages of the process involves consideration of early photoallergic dermatitis, nummular d…

Differential Diagnosis in Dermatopathology

Keratoacanthomatous verruca vulgaris vs. Verrucous keratoacanthoma

Papules on skin and mucous membranes that result from infection of keratinocytes by different types of papillomavirus and classified according to their silhouettes, to wit, papillated (verrucae vulgares on different sites such as volar skin, i.e., v…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…tic cells 1. Parakeratosis with few orthokeratotic cells 2. Hypergranulosis 2. Few, if any, granular cells in a lesion that has not been rubbed persistently 3. Epithelium thickened slightly 3. Epithelium thickened considerably 4. No abnormal ke…

Differential Diagnosis in Dermatopathology

Discussions

…sis are likely to be imposed on it. In those instances, abnormal keratocytes, a thickened epithelium, hypergranulosis, and both parakeratosis and compact orthokeratosis will be present together. Search Derm101.com for leukokeratosis and leukoplakia….

Differential Diagnosis in Dermatopathology

Dilated pore vs. Pilar sheath acanthoma

Papules on skin and mucous membranes that result from infection of keratinocytes by different types of papillomavirus and classified according to their silhouettes, to wit, papillated (verrucae vulgares on different sites such as volar skin, i.e., v…

Differential Diagnosis in Dermatopathology

Pigmented Lesions

…ytes is common. Often there are compact orthokeratosis, focal hypergranulosis, adnexal hyperplasia, dull pink globules in the epidermis, and clefts between nests/fascicles of melanocytes and keratocytes adjacent to them. Reed’s (356, 357, 3…

Differential Diagnosis in Dermatopathology

Discussions

…logic, among them being a papillated and thickened epidermis, hypergranulosis, and cells with pale cytoplasm within the epidermis. The terms “epidermolytic hyperkeratosis” and “plane wart” are not in parallel with one another,…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…dermis, either papillated or digitated 2. Thin epidermis 3. Hypergranulosis usually 3. Granular zone normal or slightly decreased in thickness 4. Epidermis sometimes hyperpigmented 4. Epidermis consistently hyperpigmented 5. Projections of elon…