Histologic Diagnosis of Inflammatory Skin Diseases

Non-bullous congenital ichthyosiform erythroderma

Non-bullous congenital ichthyosiform erythroderma Synonyms Autosomal recessive lamellar ichthyosis with normal transglutaminase levels Erythrodermic lamellar ichthyosis (ELI) Congenital ichthyosiform erythroderma Nonbullous congenital ichthyosiform…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Sclerotic Fibroma?

“Nine biopsies revealed a distinctive type of fibroma characterized by an organized pattern of interwoven fascicles of collagen bundles with a laminated or tortuous appearance, embedded in abundant mucin. A number of fibromas showed striking…

Histologic Diagnosis of Inflammatory Skin Diseases

Kimura’s disease

Kimura’s disease Synonyms Eosinophilic lymphofolliculitis Presentation stereotypical Age and sex Young men, especially Asians Distribution of lesions Head, neck, and trunk Individual lesions Firm nodules and tumors, some gigantic, above which…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Overlap Syndromes?

“Lupus erythematosus (LE) and lichen planus (LP) are two disorders affecting the skin that usually have different clinical, histopathologic, and immunofluorescent patterns. In occasional patients, however, the features of these two diseases m…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Pityrosporum Folliculitis and Demodectic Folliculitis?

“We suggest that pityrosporum folliculitis may either be due to the predisposition of the host in the presence of the Pityrosporum organism, or the pathogenicity of certain strains of the Pityrosporum organism is capable of producing follicul…

Differential Diagnosis in Dermatopathology

Discussions

Lichen planus and lichenoid discoid lupus erythematosus have many findings histopathologic in common, among them hyperkeratosis of surface epidermis and plugs of cornified cells in infundibular epidermis; individual necrotic keratocytes; a lichenoid…

Differential Diagnosis in Dermatopathology

Discussions

Lichen sclerosus et atrophicus, which is the superficial manifestation of morphea, and chronic radiation dermatitis are both fibrosing dermatitides that may resemble each other closely when viewed through the scanning objective of a conventional mic…