Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Trichodiscoma Related to the Hair Disk and Merkel-Cell Neoplasm to Merkel Cells?

…cribed first by Felix Pinkus, emerge from the junction of the infundibulum and isthmus and, in sections cut vertically, are seen to hang as cords of undifferentiated epithelial cells along the sides of the follicle and parallel to it. Because those c…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…of acantholytic dyskeratotic cells in the spinous zone of an infundibulum = Grover’s disease As a rule, Grover’s disease, like Darier’s disease, has no predilection for infundibular epidermis, favoring instead surface epidermis. Th…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…open to a short tubule that serves as both sebaceous duct and infundibulum 6. Sebaceous ducts open into one or several widely dilated infundibula 6. Sebaceous ducts enter a single infundibulum-like structure, often without a distinct intervening se…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Origin of Adnexal Neoplasms?

…s its development as a bulge or collar at the junction of the infundibulum and isthmus of the hair follicle.” Weedon D. Skin Pathology. London: Churchill Livingstone, 2002. Implicit in the thinking of many general pathologists is the assumpti…

Histologic Diagnosis of Inflammatory Skin Diseases

Granuloma faciale

…les, each producing a hair which emerges from an ostium of an infundibulum. Differential diagnosis histopathologic Erythema elevatum diutinum, for purposes practical, is identical with granuloma faciale, except for findings histologic that pertain to…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Reactive Perforating Collagenosis?

…xuberant sufficiently, “perforate” the wall of an infundibulum, resulting in neutrophils and other infundibular contents being spewed into the dermis) complicated by the effects of rubbing and scratching. In summary, much that has been wr…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…kened bundles of collagen in the upper part of the dermis, an infundibulum plugged by corneocytes, a thinned surface epidermis, and compact orthokeratosis = Morphea, fully developed  The changes shown here are those of a superficial manifestation of…

Differential Diagnosis in Dermatopathology

Discussions

…to) “bite,” but sometimes secondary to a ruptured infundibulum or an infundibular cyst. Therefore, the term dermatofibrosis describes the lesion more aptly, conveying as it does that the process is a type of fibrosing dermatitis, rather t…