Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Reactive Perforating Collagenosis?

“A case is presented exhibiting an unusual reaction of the skin to superficial trauma. In response to minor trauma, certain changes take place within the papillary layer of the corium characterized by affinity of the connective tissue for he…

Histologic Diagnosis of Inflammatory Skin Diseases

Mycosis fungoides

Mycosis fungoides Synonyms Cutaneous T-cell lymphoma Presentation stereotypical Age and Sex Adults usually, although children may be affected. Males preponderant. Distribution of lesions Often widespread, but sometimes localized to a single patch or…

Histologic Diagnosis of Inflammatory Skin Diseases

Granuloma faciale

Granuloma faciale Presentation stereotypical Age and sex Adults of both sexes Distribution of lesions Localized to the face Shape of lesions Round or oval usually Individual lesions Papules, plaques, nodules, or tumors marked on their surface often…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Origin of Adnexal Neoplasms?

“Thus one needs to bear in mind the information required of a pathologist about a particular tumour, which can be summarized as follows: 1. What is the origin of the tumour? 2. What is likely the behavior of the tumour? 3. What is the extent…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.44.1A: Perivascular dermatitis, sparse + 10.44.1B: A suprabasal cleft, acanthotic dyskeratotic cells in the spinous and granular zones, and a column of parakeratosis = Grover’s disease Changes in foci of the epidermis iden…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

10.97.1A: Perivascular and interstitial dermatitis + 10.97.1B: Neutrophils, eosinophils, lymphocytes, and plasma cells in the interstitium of the reticular dermis = Morphea, early  The changes shown represent an early stage in a longstand…