Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Subacute Cutaneous Lupus Erythematosus?

“Hydropic degeneration of the epidermal basal cell layer and mononuclear cell infiltration around dermal blood vessels and appendages are constant features of both forms of cutaneous LE. The lesions of SCLE [subacute cutaneous lupus erythema…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

ABSCESS [L. abscessus (a going away)]: Clinically, a circumscribed collection of pus and histopathologically a localized collection of neutrophils. An abscess may form in the epidermis, both surface and infundibular, eccrine ducts, dermis, and subcu…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Perivascular Dermatitis

See Figs. 5.16 A&B, 5.17 A&B, 5.18 A&B, 5.19 A&B, 5.20 A&B, 5.21 A&B, and 5.22 A&B Figure 5.16 A. Perivascular dermatitis, perivascular only, superficial. B. Perivascular dermatitis, perivascular only, superficial and…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Anagen Effluvium?

“The follicle tends to respond in an all or none fashion with the notable exception of its response to cancer chemotherapy agents. This is the only known instance in which hair is lost follicles which continue in their growing phase without b…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Subcorneal Pustular Dermatosis?

“The consistent finding in our cases of pustules in the subcorneal position provides a distinctive feature which separates this condition [subcorneal pustular dermatosis] from the others we have mentioned. We therefore prefer to regard these…

Histologic Diagnosis of Inflammatory Skin Diseases

Lymphedema

Lymphedema Presentation stereotypical Age and sex Adults usually, women more than men Distribution of lesions Distal extremities, legs more than arms; genitalia episodically Arrangement of lesions Diffuse involvement of parts, e.g., elephantiasis In…

Histologic Diagnosis of Inflammatory Skin Diseases

Advantages of the Algorithmic Method

…hemiatrophy], fasciitis with eosinophilia, tryptophan-myalgia syndrome) and progressive systemic sclerosis (acrosclerosis, diffuse systemic sclerosis, toxic oil syndrome) Deficiency diseases (including pellagra, acrodermatitis enteropathica, necroly…