Histologic Diagnosis of Inflammatory Skin Diseases

Degos’ disease (malignant atrophic papulosis)

…; disease (malignant atrophic papulosis) Synonyms Degos’ syndrome Malignant atrophic papulosis Papulosis atrophicans maligna Koehlmeier-Degos syndrome Thromboangiitis cutaneointestinalis disseminata Fatal cutaneointestinal syndrome Lethal intes…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Perivascular Dermatitis

See Figs. 5.16 A&B, 5.17 A&B, 5.18 A&B, 5.19 A&B, 5.20 A&B, 5.21 A&B, and 5.22 A&B Figure 5.16 A. Perivascular dermatitis, perivascular only, superficial. B. Perivascular dermatitis, perivascular only, superficial and…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

ABSCESS [L. abscessus (a going away)]: Clinically, a circumscribed collection of pus and histopathologically a localized collection of neutrophils. An abscess may form in the epidermis, both surface and infundibular, eccrine ducts, dermis, and subcu…

Histologic Diagnosis of Inflammatory Skin Diseases

Advantages of the Algorithmic Method

…hemiatrophy], fasciitis with eosinophilia, tryptophan-myalgia syndrome) and progressive systemic sclerosis (acrosclerosis, diffuse systemic sclerosis, toxic oil syndrome) Deficiency diseases (including pellagra, acrodermatitis enteropathica, necroly…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Anagen Effluvium?

“The follicle tends to respond in an all or none fashion with the notable exception of its response to cancer chemotherapy agents. This is the only known instance in which hair is lost follicles which continue in their growing phase without b…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Atrophoderma?

…“Follicular atrophoderma is a cutaneous marking for two syndromes: Bazex’s syndrome and chondrodysplasia punctata.” Burgdorf WHC. Scleroatrophies. In: Sams WM Jr, Lynch PJ, eds. Principles and Practice of Dermatology. New York, NY…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Subcorneal Pustular Dermatosis?

“The consistent finding in our cases of pustules in the subcorneal position provides a distinctive feature which separates this condition [subcorneal pustular dermatosis] from the others we have mentioned. We therefore prefer to regard these…

Histologic Diagnosis of Inflammatory Skin Diseases

Lymphedema

Lymphedema Presentation stereotypical Age and sex Adults usually, women more than men Distribution of lesions Distal extremities, legs more than arms; genitalia episodically Arrangement of lesions Diffuse involvement of parts, e.g., elephantiasis In…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Discoid Lupus Erythematosus versus Systemic Lupus Erythematosus? II

…c LE II. Subacute cutaneous LE A. Papulosquamous B. Annular C. Syndromes commonly exhibiting similar morphology 1. Neonatal LE 2. Complement deficiency syndrome III. Acute cutaneous LE (systemic LE with skin lesions) localized or generalized erythema…