Search Results for: keratosis

Differential Diagnosis in Dermatopathology

Discussions

Seborrheic keratosis of the acanthotic type and eccrine poroma are both benign, epithelial, exo-endophytic neoplasms comprised mostly of small, round (basaloid) cells. Melanocytes may be scattered among keratocytes in both conditions. Seborrheic ker…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Lichen planus-like keratosis Solar keratosis with lichenoid infiltrate of lymphocytes 1. Crusts often 1. No crusts in non-traumatized lesions 2. Ortho- and parakeratosis not arranged in discrete columns 2. Ortho- and parakeratosis alternate with on…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Radial Growth Phase versus Vertical Growth Phase of Melanoma?

…nity of “vertical growth phase,” or where a solar keratosis ends and a squamous-cell carcinoma begins; solar keratosis is a superficial squamous-cell carcinoma. These exercises not only are futile, but they also deter histopathologists fr…

Differential Diagnosis in Dermatopathology

Discussions

…se, which is an inflammatory process. Darier’s disease (keratosis follicularis) is a genodermatosis inherited in autosomal-dominant fashion and is not fundamentally an inflammatory disease. The lesions usually appear during the second decade of…

Histologic Diagnosis of Inflammatory Skin Diseases

Darier’s disease and simulators of it

…one, thickened in zones above suprabasal clefts Column of parakeratosis positioned above acantholytic, dyskeratotic cells that reside above a suprabasal cleft Correlation clinicopathologic The keratotic component of papules of Darier’s disease…

Histologic Diagnosis of Inflammatory Skin Diseases

Pigmented Lesions

…mal. Slight increase of melanin in the epidermis. Nevoid hyperkeratosis of the nipple (443) Broad mammillations, each formed by a subtly elevated dermal papilla, interrupted by thin epidermal rete ridges pigmented markedly. Hemorrhage Ungual and subu…

Histologic Diagnosis of Inflammatory Skin Diseases

Cells That Mediate Inflammation (Inflammatory Cells)

…benign neoplasms (two examples already cited being seborrheic keratosis, especially in the form of lichen planus-like keratosis, and a particular melanocytic nevus in the form of halo nevus) are associated with dense infiltrates of inflammatory cells…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Ichthyoses?

…ular layer is prominent in this condition. Epidermolytic hyperkeratosis consists of a clinical spectrum of disorders; generalized forms may be bullous, and localized forms may resemble linear nevi. Intracellular and intercellular edema gives the epid…

Histologic Diagnosis of Inflammatory Skin Diseases

Definition of Inflammation in Historical Perspective

…apable of inducing an inflammatory response, e.g., seborrheic keratosis that in the face of an infiltrate of lymphocytes becomes a lichen planus-like keratosis and a certain kind of compound melanocytic nevus that, consequent to effects of lymphocyte…

Dermatology Practical & Conceptual

Pseudofolliculitis barbae: a dermatoscopic correlate

…ed lines. Thick curved lines are typically seen in seborrheic keratosis. The gray and blue colors are consistent with melanin contained within the pigmented hair shaft in the dermis. According to current understanding, collagen fibrils that are prese…