Search Results for: keratosis

Differential Diagnosis in Dermatopathology

Discussions

…oroma by Pinkus in 1956, that neoplasm repeatedly was misinterpreted histopathologically as an acanthotic type of seborrheic keratosis. From time to time, poromas and seborrheic keratoses continue to pose problems in differential diagnosis…

Histologic Diagnosis of Inflammatory Skin Diseases

Definition of Inflammation in Historical Perspective

…sponse to malignant neoplasms. Even some benign neoplasms are capable of inducing an inflammatory response, e.g., seborrheic keratosis that in the face of an infiltrate of lymphocytes becomes a lichen planus-like keratosis and a certain kind of…

Histologic Diagnosis of Inflammatory Skin Diseases

Cells That Mediate Inflammation (Inflammatory Cells)

…in the skin (and in other organs) and also no small number of benign neoplasms (two examples already cited being seborrheic keratosis, especially in the form of lichen planus-like keratosis, and a particular melanocytic nevus in the form of halo…

Differential Diagnosis in Dermatopathology

Discussions

…ed Darier’s disease in regard to attributes histopathologic. The constituents histopathologic of focal acantholytic dyskeratosis are found not only to classic Darier’s disease and the variant of Grover’s disease that simulates it,…

Histologic Diagnosis of Inflammatory Skin Diseases

Darier’s disease and simulators of it

…ratoma, a type of infundibular cyst whose lining is characterized by changes throughout its circumference of acantholytic dyskeratosis, initially was called “isolated dyskeratosis follicularis,” implying a relationship with…

Histologic Diagnosis of Inflammatory Skin Diseases

Pigmented Lesions

…ested by necrotic keratocytes, some of them in clusters at times, and by changes in the cornified layer, one often being parakeratosis. Seborrheic keratosis (26, 49, 506, 507, 508, 509) An epidermis thickened by two populations of cells, namely,…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…se, not of Darier’s disease. 10.44.20A: Perivascular dermatitis, patchy lichenoid + 10.44.20B: Foci of acantholytic dyskeratosis and parakeratosis = Grover’s disease In a section comparable of Darier’s disease, acantholytic…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Ichthyoses?

…conditions reputed to be ichthyoses, but that are not. In all authentic ichthyoses, the cornified layer is thickened by orthokeratosis and is devoid of parakeratosis. The orthokeratotic cells are arranged in laminated fashion mostly and are aligned…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

keratosis with lichenoid infiltrate of lymphocytes 1. Crusts often 1. No crusts in non-traumatized lesions 2. Ortho- and parakeratosis not arranged in discrete columns 2. Ortho- and parakeratosis alternate with one another in discrete columns 3….