Histologic Diagnosis of Inflammatory Skin Diseases

Images

…r part of the dermis, telangiectases, and scant infiltrate of lymphocytes and neutrophils = Acquired epidermolysis bullosa This is but one of several expressions morphologic of acquired epidermolysis bullosa. Another simulates bullous pemphigoid and,…

Differential Diagnosis in Dermatopathology

Discussions

…opathologic in common as follows: Perivascular infiltrates of lymphocytes may involve both superficial and deep plexuses; mononuclear cells are scattered interstitially in foci in the reticular dermis; some multinucleate histiocytes (histiocytic gian…

Histologic Diagnosis of Inflammatory Skin Diseases

Toxic shock syndrome

…opathy. Findings histopathologic Early Sparse infiltrate of lymphocytes and neutrophils around venules of the superficial plexus and scattered interstitially Edema of the papillary dermis Slight spongiosis and ballooning in foci epidermal Few neutr…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Fibrosing Dermatitis

…nces it is associated with sparse perivascular infiltrates of lymphocytes, plasma cells, and eosinophils has been called to attention in the past few years, namely, nephrogenic fibrosing dermopathy, a condition that, for practical purposes, comes int…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…oid + 10.103.1B: Infiltrate of histiocytes, plasma cells, lymphocytes, and neutrophils, edema of the papillary dermis, and neutrophils in the acanthotic epidermis, including in a broad zone of parakeratosis = Syphilis, secondary  A psoriasiform l…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…erstitial dermatitis, interface, vacuolar + 10.21.1B: Few lymphocytes, abundant mucin, an epidermis thin focally, and parakeratosis = Dermatomyositis A paltry infiltrate of inflammatory cells helps in differentiation of dermatomyositis from class…

Histologic Diagnosis of Inflammatory Skin Diseases

Persistent light reaction

…cial and deep perivascular and patchy lichenoid infiltrate of lymphocytes, plasma cells, and eosinophils; some lymphocytes may be larger than normal Papillary dermis thickened also by coarse bundles of collagen disposed in vertical streaks Plump, ste…

Histologic Diagnosis of Inflammatory Skin Diseases

Post-inflammatory pigmentary alteration

…of concavity. Findings histopathologic Early Infiltrate of lymphocytes around venules of the superficial plexus and along the dermoepidermal junction in conjunction with vacuolar alteration Few melanophages scattered in the papillary dermis Fully…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Lymphocytic Infiltration of Jessner?

…around vessels and/or appendages. The infiltrates consist of lymphocytes, mostly small ones, and usually a few histiocytes and plasma cells.” Jessner M, Kanof NB, Orfuss AJ. Lymphocytic infiltration of the skin. Arch Dermatol 1953;68:447&#821…