Search Results for: melanocytes

Atypical dermoscopic presentation of an acral congenital melanocytic nevus in an adult: parallel ridge pattern and its histologic correlation

Atypical dermoscopic presentation of an acral congenital melanocytic nevus in an adult: parallel ridge pattern and its histologic correlation

…r-cut congenital-like features. (B) (40x H&E stain) An intradermal combination of type C and dendritic (blue nevus-like) melanocytes. (C) (40x H&E stain) Striking acrosyringial and periductal distribution. (D) (20x H&E stain) Mainly…

When all you have is a dermatoscope—start looking at the nails

When all you have is a dermatoscope—start looking at the nails

…continuous, longitudinal pigmented streaks (longitudinal melanonychia) may either be caused by a benign activation of matrix melanocytes (e.g., as a result of trauma, inflammation, or adverse drug reactions) or by a true melanocytic proliferation…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Changing Mole?

…nge independently should be cause for alarm.” Rhodes AR. Neoplasms: benign neoplasias, hyperplasias, and dysplasias of melanocytes. In: Fitzpatrick TB, Eisen AZ, Wolff K, et al., eds., Dermatology in general medicine. 4th ed. New York:…

Histologic Diagnosis of Inflammatory Skin Diseases

Introduction

…idual components of the skin, namely, epidermis, hair follicles, sebaceous units, apocrine units, eccrine units, nail units, melanocytes, Langerhans” cells, Merkel cells, structures of the dermoepithelial interface, blood vessels, lymphatics,…

Balloon cell melanoma in primary care practice: a case report

Balloon cell melanoma in primary care practice: a case report

…he second component, by contrast, was comprised of centrally positioned atypical aggregates of grossly distended epithelioid melanocytes, exhibiting a pseudo-xanthomatous balloon cell change in their cytoplasm, and pleomorphic vesicular nuclei with…

Spitz/Reed nevi: a review of clinical-dermatoscopic and histological correlation

Spitz/Reed nevi: a review of clinical-dermatoscopic and histological correlation

…f superficial dermal melanophages is thought to be responsible for the bluish background (HE, x20). Pigmented spindle-shaped melanocytes predominate in well-demarcated junctional nests (insets, x100 and x200). [Copyright: ©2016 Pedrosa et al.]…

Histologic Diagnosis of Inflammatory Skin Diseases

Post-inflammatory pigmentary alteration

…in which inflammatory cells dislodged melanin from keratocytes in the basal layer of the epidermis especially, but also from melanocytes there, the melanin lost having been garnered by macrophages. Vacuolar alteration present still along the…

A tiny invasive melanoma: a case report with dermatoscopy and dermatopathology

A tiny invasive melanoma: a case report with dermatoscopy and dermatopathology

…opathologic assessment (Figure 2 composite) showed a small, but asymmetric, nested and single cell proliferation of atypical melanocytes along the dermoepidermal junction with scattered single cell intraepithelial upward spread. There was limited…