Differential Diagnosis in Dermatopathology

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Dermatitis herpetiformis Bullous pemphigoid

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Dermatitis herpetiformis Bullous pemphigoid 1. Subepidermal blister that contains neutrophils mostly; eosinophils in variable number, present, too, about 72 hours after onset 1. Subepidermal blister that contains eosinophils mostly; neutrophils…

Differential Diagnosis in Dermatopathology

Urticarial reaction to an arthropod assault vs. Urtica

An inflammatory process in pregnant women near term that consists of urticarial papules and plaques, especially on the trunk and particularly in association with lesions of striae atrophicantes, the lesions disappearing shortly after parturition….

Dermatology Practical & Conceptual

Epidermal multinucleated giant cells are not always a histopathologic clue to a herpes virus infection: multinucleated epithelial giant cells in the epidermis of lesional skin biopsies from patients with acantholytic dermatoses can histologically mimic a herpes virus infection

…K. Generalized herpes simplex infection complicating bullous pemphigoid. Br j Dermatol. 1995;132:484-6. 33. Nikkels AF, Delvenne P, Herfs M, Pierard GE. Occult herpes simplex virus colonization of bullous dermatitides. Am J Clin Dermatol. 2008;9:1…

Differential Diagnosis in Dermatopathology

Discussions

…is the case commonly in dermatitis herpetiformis and bullous pemphigoid, and uncommonly in pemphigus vulgaris and polymorphous light eruption. Biopsy of the hive-like lesions in those four diseases produces a specimen from which sections of tissue d…

Histologic Diagnosis of Inflammatory Skin Diseases

Parasitic infestations

…by arthropods, certain infestations by parasites, and bullous pemphigoid/herpes gestationis. Laboratory confirmation The parasite is demonstrated in tissues or in blood. Peripheral eosinophilia is present. Cause and mechanism Various distinctive pa…

Histologic Diagnosis of Inflammatory Skin Diseases

Erythema figuratum

…ne another, among those being the urticarial stage of bullous pemphigoid and, at times, even urticaria itself, to say nothing of psoriasis and mycosis fungoides that, episodically, present themselves as annular, arcuate, and polycyclic lesions. In sh…

Differential Diagnosis in Dermatopathology

Images

Urticaria Urticarial lesions of bullous pemphigoid