Differential Diagnosis in Dermatopathology

Urticarial reaction to an arthropod assault vs. Urtica

An inflammatory process in pregnant women near term that consists of urticarial papules and plaques, especially on the trunk and particularly in association with lesions of striae atrophicantes, the lesions disappearing shortly after parturition….

Differential Diagnosis in Dermatopathology

Images

Dermatitis herpetiformis Bullous pemphigoid

Dermatology Practical & Conceptual

Epidermal multinucleated giant cells are not always a histopathologic clue to a herpes virus infection: multinucleated epithelial giant cells in the epidermis of lesional skin biopsies from patients with acantholytic dermatoses can histologically mimic a herpes virus infection

Abstract Background: Multinucleated giant cells in the epidermis can either be epithelial or histiocytic. Epithelial multinucleated giant cells are most often associated with herpes virus infections. Purpose: To review the histologic differential di…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Dermatitis herpetiformis Bullous pemphigoid 1. Subepidermal blister that contains neutrophils mostly; eosinophils in variable number, present, too, about 72 hours after onset 1. Subepidermal blister that contains eosinophils mostly; neutrophils…

Differential Diagnosis in Dermatopathology

Discussions

In an urticarial reaction to an assault by an arthropod and in lesions of true urtica, the infiltrate of inflammatory cells is mixed, contains at least lymphocytes and usually eosinophils, and is accompanied by extravasated erythrocytes and edema of…

Histologic Diagnosis of Inflammatory Skin Diseases

Parasitic infestations

Parasitic infestations Presentation stereotypical Age and sex No predilection for age or sex; occurring chiefly in the tropics Distribution of lesions Localized usually to one site anatomic; some infestations parasitic are associated with lesions wi…

Histologic Diagnosis of Inflammatory Skin Diseases

Erythema figuratum

Erythema figuratum Synonyms Erythema figuratum perstans Figurate erythema Annular erythema Presentation stereotypical Age and sex Adults of both sexes, but women especially Distribution of lesions Localized or widespread, trunk and proximal extremit…

Differential Diagnosis in Dermatopathology

Images

Urticaria Urticarial lesions of bullous pemphigoid