Histologic Diagnosis of Inflammatory Skin Diseases

Junctional epidermolysis bullosa

…is bullosa. Dystrophic epidermolysis bullosa heals with white scars that take the form of papules (albopapuloid) and with milia, findings not present in junctional epidermolysis bullosa. Findings histopathologic Fully developed Sparse perivascular i…

Differential Diagnosis in Dermatopathology

Discussions

…florid, it may eventuate, in years, in pitted or hypertrophic scars or in tenacious sinus tracts of “acne conglobata.” Comedones traditionally have been described as “open” (blackheads) or “closed” (whiteheads). In…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Diabetic Dermopathy?

…tibiae, and those lesions heal with atrophic, hyperpigmented scars that, on examination histopathologic, are seen to consist of sclerosis accompanied by dilated venules in the upper part of the dermis above which is a thinned, hyperpigmented epiderm…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Hyalin?

…more difficult to analyze. Collagenous fibrous tissue in old scars may appear hyalinized … In long-standing hypertension and diabetes mellitus, the walls of arterioles, especially in the kidney, become hyalinized …With hematoxylin and eosin stains,…

Differential Diagnosis in Dermatopathology

Discussions

…t site of treatment. The changes seen clinically are atrophic scars, loss of hair, and presence of telangiectases and hyper- and hypopigmentation. Keratoses, known as radiation keratoses, may develop at sites of chronic radiodermatitis; like solar ke…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…bcutaneous fat, a consequence of trauma at this site. Changes similar to those of nodular fasciitis are met with in scars and dermatofibromas, both of which also represent patterns morphologic of fibrosing inflammation in response to injury….

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Urticarial Vasculitis?

…are hemorrhagic, pustules, and ulcers. The latter resolve as scars. In short, the range of presentations clinical in cutaneous vasculitis is broad and, therefore, it is parochial in the extreme to describe that process protean by but a single type o…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Keratosis Lichenoides Chronica?

…trauma resulting in formation of linear bands of hypertrophic scars.” Mehregan AH, Heath LE, Pinkus H. Lichen ruber moniliformis and lichen ruber verrucosus et reticularis of Kaposi. J Cutan Pathol 1984;11:2–11. “In Kaposi’…