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Therapeutic Strategies in Dermatology
Bruce U. Wintroub, M.D., Timothy G. Berger, M.D. |
© 20022006 Ardor Scribendi, Ltd. All rights reserved.
Acne Keloidalis Nuchae
Dermatitis Papillaris Capillitii
This disease primarily
affects the nape of the neck of black men and is a form of follicular
inflammation with excessive scarring which represents a keloidal
reaction to prior or ongoing folliculitis. The strategy of therapy
is to treat active folliculitis, if present, and to reduce hypertrophic
hair fragment induced scars. Patients may or may not form hypertrophic
scars or keloids at other sites.
First steps
- If
active folliculitis is present, culture the lesions for bacteria
and prescribe an oral antibiotic such as tetracycline 500 mg twice
daily, doxycycline or minocycline 50-100 mg twice daily.
- To prevent folliculitis, treat topically
with benzoyl peroxide gel or wash applied every day to the affected
area.
- To reduce scar formation, inject intralesional
triamcinolone acetonide 5-10 mg per cc to individual hypertrophic
lesions at 2- to 4-week intervals.
Ancillary Measures
- Patients
should avoid greasy hair products.
- Neck hair should not be trimmed short.
Next steps
- If
active folliculitis persists, reculture the lesions and chose an
alternative antibiotic as indicated by the result of culture and
sensitivity.
- If papules do not regress, increase
the strength of the intralesional steroid to 20 mg per cc initially
and then to 40 mg per cc if necessary.
- It may be necessary to continue topical
benzoyl peroxide and/or appropriate antibiotic therapy
indefinitely.
Surgical Therapy
Most persistent or extensive cases are best
managed by surgical techniques.
- Few
small papules: Individual lesions may be shaved off or preferably punched
out and sutured closed.
- Large plaques: Larger lesions may be
removed by surgical excision. Scalpel or laser surgery may be used.
Healing may be by secondary intention or by primary closure. If
the defect is closed primarily, tension should be minimal to prevent
a spread scar and keloid formation. A tissue expander may provide
adequate tissue for primary closure of large lesions.
- If surgical removal is performed, intralesional
injection of triamcinolone into the scar may be required postoperatively.
Pitfalls
- Avoid
surgical procedures in persons who form keloids at other sites.
- Discontinuation of the topical benzoyl
peroxide and/or oral antibiotics may lead to a reactivation
of the folliculitis.
© 20022006 Ardor Scribendi, Ltd. All rights reserved.