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Therapeutic Strategies in Dermatology

Melanoma: Treatment

Treatment Initial therapy First-line: Surgical excision For diagnosis, complete excisional biopsy with minimal margins, pathologically evaluated at multiple levels to determine the tumor thickness, ulceration, mitotic index, evidence of regression,…

Therapeutic Strategies in Dermatology

Erythema Annulare Centrifugum: Overview

Gyrate Erythemas, Figurate Erythemas, and Migratory Erythemas Gyrate erythemas are reactive processes. The therapeutic strategy is to determine and treat the underlying cause, and the cutaneous reaction is then cured. Underlying malignancy; dermatop…

Therapeutic Strategies in Dermatology

Melanoma: Clinical Cases

Clinical Cases Case 1 37-year-old woman with >75 atypical nevi No family history of atypical nevi or melanoma Presents for an evaluation of a “new mole” that rapidly developed on the right leg A full-body skin examination is performed and doe…

Therapeutic Strategies in Dermatology

Erythema Multiforme: Treatment

Treatment Initial therapy First-line treatment is supportive care. Diagnostic management should entail consideration of a skin biopsy and a reasonable search for potential triggers that can be eliminated or treated. Diagnostic considerations inclu…

Therapeutic Strategies in Dermatology

Melanoma: Key Points

Key Points The therapy of malignant melanoma is determined by the histopathologic features (tumor thickness, depth of invasion, ulceration, regression, mitotic index), by the location of the tumor, by the presence of regional or distant metastases,…

Therapeutic Strategies in Dermatology

Melanoma: Principles of Management of Melanoma

Principles of Management of Melanoma Prognosis is largely determined by histologic features of the primary melanoma (depth of invasion and/or the degree to which the tumor has invaded the skin, as well as ulceration and mitotic index). The major ind…

Therapeutic Strategies in Dermatology

Facial Melanosis, Melasma: References

References Rajartnam R, Halpern J, Salim A, Emmett C (2010) Interventions for melasma, Cochrane Database of Systematic Reviews, 7: ArtCD003583. Pandya AG et al (2011) Reliability assessment and validation of the Melasma Area and Severity Index (MASI…

Therapeutic Strategies in Dermatology

Venous Stasis: Treatment

Treatment Stasis dermatitis First-line therapy: The first-line therapy for stasis dermatitis includes control of edema, if possible, and use of an anti-inflammatory topical medication such as a medium potency topical corticosteroid. Stasis dermati…

Therapeutic Strategies in Dermatology

Cheilitis Granulomatosa: Overview

Melkersson-Rosenthal Syndrome Cheilitis granulomatosa is sudden onset of swelling of the lips which progresses to chronic enlargement. The Melkersson-Rosenthal syndrome diagnosis is made when lip enlargement is accompanied by facial paralysis or par…

Therapeutic Strategies in Dermatology

Xerosis: Overview

Overview Xerosis can reflect an inherited tendency toward dry skin as it is seen as a part of the atopic diathesis, or it can occur in normal individuals as a consequence of frequent bathing with excessively hot water and harsh soaps and/or after pr…

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