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Key Points Actinic keratoses (AKs) are the most common epithelial precancerous skin lesions. They present as scaly, erythematous, ill-defined papules on sun-exposed areas. A small percentage of AKs may progress to non-melanoma skin cancer (NMSC) over a lifetime. Therapy is determined by anatomic location and number of lesions. Introduction Actinic keratoses (AKs) typically present as […]