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Overview This sexually transmitted disease is caused by the gram-negative bacterium Klebsiella granulomatis. Treatment is directed against the causative microorganism. Treatment First Steps Azithromycin 1 gram orally once weekly for 6 weeks, or until the ulcer has healed (but for at least 3 weeks). Alternative Steps Azithromycin 500 mg daily for 7 days. Subsequent Steps […]