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Overview Ichthyosis results from abnormal retention and/or production of the stratum corneum layer of the epidermis. Acquired ichthyosis can be a cutaneous manifestation of an underlying disease (e.g., malignant neoplasm, metabolic disorder, malabsorption). The genetic ichthyoses comprise a heterogeneous group of disorders that are either limited to the skin (primary ichthyoses) or part of a […]