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Initial Evaluation: Squamous Cell Carcinoma Predisposing factors for squamous cell carcinoma (SCC) include precursor lesions (actinic keratosis [AK], BowenÂ’s disease), UV exposure, ionizing radiation, environmental carcinogens (arsenic), immunosuppression, scars, burns, human papillomavirus (HPV), genodermatoses (xeroderma pigmentosum, albinism). Squamous cell carcinomas of the skin have several key clinical features: Hyperkeratotic, erythematous papules and plaques Have superficial […]