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Overview Prurigo nodularis is a morphologic lesion that is a consequence of severe and repeated scratching of one area. In most patients it is secondary to an underlying pruritic condition such as photosensitive dermatitis, renal failure, or neuropathic pruritus due to nerve impingement (brachioradial pruritus). Rarely, bullous pemphigoid may present as prurigo nodularis (pemphigoid nodularis). […]