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Treatment First-line therapy: Therapy is usually not required; any treatment is directed towards symptoms only. Skin-directed therapy for patients with vesicobullous lesions and/or pruritus: Antihistamines (e.g., hydroxyzine 10-25 mg t.i.d. [such as Atarax], diphenhydramine 25-50 mg t.i.d. [such as Benadryl], or chlorpheniramine 4-16 mg/day) can be used to alleviate pruritus. For pediatric cases, hydroxyzine syrup […]