Search Results for: amyloid

A Clinical Atlas of 101 Common Skin Diseases


A condition in which deposits of a fibrillary protein (amyloid) appear in the skin as macules, papules, and nodules consequent to the effects of local factors, or as patches (which may be purpuric), plaques, nodules, and tumors as a result of a systemic disease like myeloma.

Therapeutic Strategies in Dermatology

Sarcoidosis: Key Points

…lammatory response, representing the onset of the disease. Putative antigens include an unknown autoantigen, misfolded serum amyloid A proteins, infectious agents (including mycobacteria or Propionibacterium acnes), particulate matter, or heavy…

Histologic Diagnosis of Inflammatory Skin Diseases

Macular and papular (lichenoid) amyloidosis-Cutaneous solely

…ulate in dermal papillae, causing those structures to widen. As a rule, melanophages are present in company with globules of amyloid. Macular amyloidosis can be misread histopathologically as “postinflammatory pigmentary alteration” if…

Differential Diagnosis in Dermatopathology


…losely with the deposits of homogeneous material. In fact, it is likely that fibrocytes are responsible for the formation of amyloid in lichen amyloidosis and of colloid in colloid milium. Because of the highly characteristic attributes…

Notalgia paresthetica: the unreachable itch

Notalgia paresthetica: the unreachable itch

…ore not surprising to see amyloid deposits in pruritic NP lesions that have been present for years. However, the presence of amyloid can make the distinction from macular amyloidosis difficult, as there is considerable overlap of these two entities…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…the epidermis often 3. No necrotic keratocytes in the epidermis 4. Rete ridges form pincers around subepidermal deposits of amyloid 4. No pincers formed by rete ridges 5. Amyloid situated in widened dermal papillae 5. Colloid positioned in the…

Histologic Diagnosis of Inflammatory Skin Diseases


…and interstitial dermatosis, superficial + 11.3.3B: Globules in the upper part of the dermis in company with melanophages = Amyloidosis, papular Amyloid, seen as globules in the upper part of the dermis, is highlighted by crystal violet stain….

Resolving Quandaries in Dermatology, Pathology & Dermatopathology


…e apoptosis in infantile myofibromatosis. Am J Pathol 1994; 144:480-85. “Amyloid-hyaline-colloid deposition. Disorder: Amyloidoses Familial amyloidotic neuropathy ß2-Microglobulin amyloid Colloid milium Hyalinosis cutis et mucosae Porphyria…

Widespread pruritic papules on the trunk and extremities

Widespread pruritic papules on the trunk and extremities

…2008;33(3):191-3. CrossRef 6. Apaydin R, Gurbuz Y, Bayramgurler D, Müezzinoglu B. Bilen N. Cytokeratin expression in lichen amyloidoisus and macular amyloidosis. J Eur Acad Dermatol Venereol. 2004;18(3):305-9. CrossRef 7. Grimmer J, Weiss T, Weber…