Search Results for: clone

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Paraneoplastic Pemphigus?

…nocyte lambda gt 11 cDNA expression library by the immunoperoxidase method with serum IgG from a PNP patient. . . . A single clone, called here the PNP clone, producing a fusion protein that reacted strongly with the patient’s IgG, was further…

Billings SD, Cotton J. Inflammatory Dermatopathology. A Pathologist’s Survival Guide. New York: Springer Science + Business Media LLC, 2011

Billings SD, Cotton J. Inflammatory Dermatopathology. A Pathologist’s Survival Guide. New York: Springer Science + Business Media LLC, 2011

…t be covered as a separate section in a book on inflammatory dermatoses, as this is an abnormal growth and accumulation of a clone of mast cells, and therefore, is best categorized as a neoplastic, and not inflammatory, disorder. The same holds true…

Hypopigmented atypical Spitzoid neoplasms (atypical Spitz nevi, atypical Spitz tumors, Spitzoid melanoma): a clinicopathological update

Hypopigmented atypical Spitzoid neoplasms (atypical Spitz nevi, atypical Spitz tumors, Spitzoid melanoma): a clinicopathological update

…features. Histopathologically, it differs from atypical Spitz nevus or Spitz tumor by showing a non-Spitzoid cytomorphologic clone arising in the context of a Spitzoid lesion. Such a highly unusual occurrence can be detected even clinically and…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Blaschkitis?

…tributed along the primitive streak and reflect the dorsoventral outgrowth during embryogenesis of two functionally distinct clones. Happle maintains that the transverse clonal proliferation of cells interferes with the longitudinal growth as well…

Eosinophilic dermatosis of hematologic malignancy mimicking varicella zoster infection: report in a woman with chronic lymphocytic leukemia and review of the literature

Eosinophilic dermatosis of hematologic malignancy mimicking varicella zoster infection: report in a woman with chronic lymphocytic leukemia and review of the literature

…ions in patients with CLL and eosinophilic dermatosis of hematologic malignancy include Richter transformation and malignant clone expansion [2,10]. An underlying state of immunosuppression is postulated as the cause for these occurrences….