Search Results for: hyaline

Therapeutic Strategies in Dermatology

Livedo / Livedoid Vasculopathy / Atrophie Blanche: Initial Evaluation

…livedoid vasculopathy, the histopathological findings reflect the stage of the lesion sampled. Early lesions typically show hyaline thrombi within small vessels in the mid and upper dermis and endothelial cell proliferation. A perivascular…

Therapeutic Strategies in Dermatology

Livedo / Livedoid Vasculopathy / Atrophie Blanche: Clinical Case

…able pulses bilaterally Minimal edema and varicosities Rest of cutaneous exam is unremarkable Biopsy is performed that shows hyaline thrombi in small vessels in the mid and upper dermis. No vasculitis is seen Diagnosis: Livedoid vasculopathy Given…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Hyalin?

…LeBoit PE, Robinson JK, et al., eds. Cutaneous Medicine and Surgery. Philadelphia: W. B. Saunders Company, 1996:1153. “Hyaline change The term hyaline is widely used as a descriptive histologic term rather than a specific marker for cell…

Histologic Diagnosis of Inflammatory Skin Diseases

Confusing Terms (to be Avoided Scrupulously)

…certain diseases, e.g., “toxic hyaline” for erythema elevatum diutinum. It is now appreciated that “toxic hyaline” is just fibrin. “Hyaline globules” is a name given to degenerating erythrocytes lodged in…

Histologic Diagnosis of Inflammatory Skin Diseases

Errors and Reasons

…d the urticarial stage of bullous pemphigoid, they are mere suppositions at best and flawed interpretations at worst. Error: Hyaline is a specific substance. Reason: Hyaline, in general, refers to brightly eosinophilic refractile material and is not…

Malignant cylindroma in a patient with Brooke-Spiegler syndrome

Malignant cylindroma in a patient with Brooke-Spiegler syndrome

…, ×40. [Copyright: ©2015 Kazlouskaya et al.] Figure 3. Small irregular aggregates of the cylindrocarcinoma, some are without hyaline sheath. Loss of jigsaw pattern. H&E stained sections, ×100. [Copyright: ©2015 Kazlouskaya et al.] Figure 4….

Waldenström macroglobulinaemia presenting as tingling ulcers on the feet

Waldenström macroglobulinaemia presenting as tingling ulcers on the feet

…er examination, papules were noted on the knees. (C) Biopsy from a knee papule showed homogeneous extravascular eosinophilic hyaline deposits throughout the papillary and reticular dermis (H&E 40x). (D) IgM stain demonstrates the extravascular…