Search Results for: karyolysis

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…r matrical cells actually represent ghosts of nuclei of cornified cells that fail in their attempt to produce a normal hair. Karyolysis is thought to result from progressive dissolution of chromatin as a consequence of the hydrolytic action of…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…re is specific for external trauma caused by a sharp instrument, such as a fingernail. The evidence of epidermal necrosis is karyolysis surrounded by pink cytoplasm. 10.23.13A: Fibrosing dermatitis + 10.23.13B: Fibrocytes scattered among thickened…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Apoptosis?

…rucial findings nuclear, namely, pyknosis (shrunken hyperchromatic nuclei), karyorrhexis (“dust” of nuclei), and karyolysis (ghosts of nuclei). So-called apoptotic cells show two of the three signs of necrosis, namely, pyknosis and…

Histologic Diagnosis of Inflammatory Skin Diseases

Errors and Reasons

…assic Virchowian pathology, necrosis is characterized cytopathologically by three signs, namely, pyknosis, karyorrhexis, and karyolysis; apoptosis is typified by pyknosis and karyorrhexis, and, therefore, logic compels that it fulfills criteria for…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

…sis with Evidence of Ballooning, But without Signs of Vesiculation An epidermis that exhibits nuclei characterized mostly by karyolysis and cytoplasm typified by eosinophilia across a front of at least several millimeters. Click image to enlarge. +…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…heir nuclei being pyknotic. At a later time, no hint of outlines of glandular cells is discernible, the cells of them being necrotic totally. Note also necrosis of the epidermis as indicated by karyolysis….