Search Results for: sclerema neonatorum

Histologic Diagnosis of Inflammatory Skin Diseases

Sclerema neonatorum

…necrotic fat sometimes Diffuse fibroplasia in zones of necrosis of fat Correlation clinicopathologic Plaques and nodules of sclerema neonatorum result from thickening of the subcutaneous fat consequent to increase in the size of nearly every…

Histologic Diagnosis of Inflammatory Skin Diseases

Poststeroid panniculitis

…ferent causes. Subcutaneous fat necrosis and its lookalike, poststeroid panniculitis, are different histopathologically from sclerema neonatorum, a condition that is not truly a panniculitis, devoid as it is initially of an infiltrate of…

Histologic Diagnosis of Inflammatory Skin Diseases

Subcutaneous fat necrosis of the newborn

…s, thighs, shoulders, back, or arms Individual lesions Dusky-red nodules Course Self-limited Differential diagnosis clinical Sclerema neonatorum is manifested by diffuse hardening of the skin of debilitated newborns. Findings histopathologic Early…

Histologic Diagnosis of Inflammatory Skin Diseases


…id panniculitis, on one hand and sclerema neonatorum on the other. The crystals shown are present in macrophages, whereas in sclerema neonatorum they are present in adipocytes almost entirely. 10.101.2A: Panniculitis, lobular + 10.101.2B: Crystals…

Histologic Diagnosis of Inflammatory Skin Diseases

Toxic erythema of the newborn

…rn infants in the first 5 days of life. Hautarzt 2000;51(6):396–400. Marchini G, Ulfgren AK, Lore K, et al. Erythema toxicum neonatorum: an immunohistochemical analysis. Pediatr Dermatol 2001;18:177–87. Meyerhof E, Lypolt-Krajaniovic M. Das erythema…

Histologic Diagnosis of Inflammatory Skin Diseases

Cold panniculitis

…rs in the first few weeks of life of healthy newborns as red-purple nodules on the cheeks, back, buttocks, arms, and thighs. Sclerema neonatorum affects infants debilitated by a severe disease underlying, e.g., catastrophic dehydration secondary to…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Subcorneal Blistering Diseases?

…aphylococcal scalded skin syndrome Bullous impetigo Friction blister Pemphigus foliaceus and erythematosus .Erithema toxicum neonatorum” Rapini R. Clinical and pathologic differential diagnosis. In: Bolognia JL, Jorizzo JL, Rapini RP, eds….

Differential Diagnosis in Dermatopathology


…ubstances); scleromyxedema, known also as papular mucinosis and lichen myxedematosis, is an expression of a paraproteinemia; sclerema neonatorum is a consequence of enzymatic abnormalities in adipocytes that result in an increased ratio of saturated…