Search Results for: silica%20granuloma

Histologic Diagnosis of Inflammatory Skin Diseases

Silica granuloma

…filtrate of histiocytes that have foamy cytoplasm. Whenever a histopathologist encounters a sarcoidal granuloma in the skin, silica must be considered in the differential diagnosis. A clue helpful to diagnosis histopathologic is linear knife marks…

Histologic Diagnosis of Inflammatory Skin Diseases

Foreign body reaction

…shaped like a Maltese cross. Beryllium and zirconium, as well as silica, elicit sarcoidal granulomatous responses, but only silica, usually in the form of glass, polarizes. Tattoos, mercury especially, may provoke a sarcoidal granulomatous…

Histologic Diagnosis of Inflammatory Skin Diseases

Sarcoidosis

…tial diagnosis histopathologic Granulomas evoked by beryllium and zirconium are indistinguishable from those of sarcoidosis. Silica granuloma is distinguishable from sarcoidosis by the presence of crystalline particles in histiocytes, particularly…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Scleroderma?

…induced scleroderma and scleroderma renal crisis. South Med J 1998;91(10):961–63. “Experimental studies show that silica dust is able to activate microvascular endothelial cells, mononuclear cells from peripheral blood, and dermal…

Differential Diagnosis in Dermatopathology

Discussions

…own. Granulomatous dermatitides that may be indistinguishable histopathologically from sarcoidosis are brought into being by silica, beryllium, and zirconium. Silica is made more apparent when sections are examined by polarized light….

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…tuberculoid. Sarcoidal granulomas are found not only in sarcoidosis, but also in foreign body responses to materials such as silica and beryllium. Tuberculoid granulomas are encountered in infectious diseases besides tuberculosis, among those being…

Histologic Diagnosis of Inflammatory Skin Diseases

Leprosy

…dal granulomas because they are seen stereotypically in sarcoidosis, appear also in conditions as remote from sarcoidosis as silica granulomas and berylliosis. In a sense, lepromatous leprosy at times presents itself histopathologically as a type of…

Histologic Diagnosis of Inflammatory Skin Diseases

Cells That Mediate Inflammation (Inflammatory Cells)

…display necrosis in the center of clusters of epithelioid cells. Sarcoidal granulomas form in response to materials such as silica and beryllium, and, paradoxically, albeit uncommonly, in response to Mycobacterium tuberculosis and to other…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…us + 10.38.9B: Histiocytes, many of them multinucleate, contiguous with suture = “Suture granuloma” Suture, like silica and cellulose, is an inciter common of foreign body granulomatous inflammation in the skin. 10.38.10A: Nodular…