Search Results for: tuberous sclerosis

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Therapeutic Strategies in Dermatology

Livedo / Livedoid Vasculopathy / Atrophie Blanche: Initial Evaluation

…arction of the dermis with frank ulceration may be seen. Finally, if scarred areas are sampled, epidermal atrophy and dermal sclerosis are seen. Further work-up (to evaluate for a potential underlying etiology) should be determined based on the…

Therapeutic Strategies in Dermatology

Balanitis: Overview

…ypes is discussed separately. Certain specific skin diseases (e.g., Reiter’s disease, psoriasis, lichen planus, lichen sclerosis et atrophicus, syphilis, and scabies) may affect the glans penis preferentially. A total skin examination to rule…

Therapeutic Strategies in Dermatology

Lichen Sclerosus et Atrophicus: Overview

Kraurosis Vulvae / Balanitis Xerotica Obliterans Patients can be divided into three clinical groups for management: prepubertal children, adults with anogenital disease, and adults with extragenital disease. Prepubertal children at times have…

Therapeutic Strategies in Dermatology

Livedo / Livedoid Vasculopathy / Atrophie Blanche: Key Points

…inidine/quinine, interferon beta, bismuth, warfarin) Neurological disorders (Sneddon syndrome, Parkinson’s disease, multiple sclerosis, reflex sympathetic dystrophy) The term, livedoid vasculopathy (LV), is used when frank purpura, necrosis and…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Scleroderma?

…f porphyria cutanea tarda) Linear (en coup de sabre and facial hemiatrophy) Both cutaneous and systemic Progressive systemic sclerosis Diffuse systemic sclerosis CREST syndrome Chemically induced, e.g., l-tryptophan-related eosinophilia-myalgia…

Histologic Diagnosis of Inflammatory Skin Diseases

Radiation dermatitis and panniculitis

…hrombi that plug vessels in the reticular dermis. Malignant epithelial neoplasms seem to develop secondary to the effects of sclerosis on the epidermis, analogous to the situation in sclerosis of lichen sclerosus et atrophicus, chronic discoid lupus…

Histologic Diagnosis of Inflammatory Skin Diseases

Lichen sclerosus et atrophicus

…cause of marked thickening by alterations in collagen of the upper part of the dermis Papillary dermis thickened markedly by sclerosis Telangiectases in the zone of sclerosis Uppermost part of the reticular dermis displays crowded, thickened bundles…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…ance of the bundles having become blended (“homogenization”) and by marked decrease in the number of fibrocytes. Sclerosis usually indicates that fibroplasia has been longstanding. Examples of sclerosis are the thickened papillary dermis…

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