Search Results for: x-linked%20ichthyosis

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Therapeutic Strategies in Dermatology

Ichthyoses/Disorders of Cornification: Overview

…e. The hydroxy acids (i.e., lactic acid lotion, ammonium lactate gel, or glycolic acid lotion) are especially efficacious in Xlinked ichthyosis, and may be the only specific therapy needed for this disease. Patients with acquired ichthyosis need to…

Therapeutic Strategies in Dermatology

Bullous Pemphigoid: Key Points

…with urticarial plaques with bullae, usually on the abdomen, and proximal thighs, and can involve the rest of the trunk or extend to the extremities as well. Oral involvement is uncommon, with 10-25% of patients having oral erosions due to BP….

Therapeutic Strategies in Dermatology

Pediculosis (Lice): Treatment

…be treated accordingly. Topical steroids and oral antihistamines may be required for days to weeks to control pruritus. If extensive excoriation is noted, the patient should be carefully examined or tested for bacterial superinfection and treated…

Histologic Diagnosis of Inflammatory Skin Diseases

Histiocytosis X

…is, ultimately, of attributes cytopathologic alone, e.g., infection by herpesvirus, molluscum contagiosum, and histiocytosis X. Whether histiocytosis X is an inflammatory or a neoplastic process has been a matter of debate. In our view,…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology


…chthyosiform dermatoses. Arch Dermatol 1966;94:113–26. “There are four major types of ichthyosis: ichthyosis vulgaris, Xlinked ichthyosis, ichthyosis congenita and epidermolytic hyperkeratosis (bullous ichthyosiform erythroderma). In…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology


…ko’s lines. Happle, in 1993, demonstrated that the lines of Blaschko become manifest in heterozygous states of various Xlinked gene defects, such as incontinentia pigmenti, Xlinked hypohidrotic ectodermal dysplasia, and focal dermal…

Differential Diagnosis in Dermatopathology


…. As in all ichthyoses, the scales are thickest on the legs. Histopathologically, the scales of both ichthyosis vulgaris and Xlinked ichthyosis consist entirely of cells orthokeratotic, none being parakeratotic. The turnover time of the epidermis…

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