Clinical Reference / Diagnosis in Dermatopathology / Dermatofibrosarcoma protuberans (inflammatory and neoplastic disease)

Dermatofibrosarcoma protuberans (inflammatory and neoplastic disease)

Differential Diagnosis

This sessile, slightly variegated nodule is a typical schwannoma.

This large, multilobulated, skin-colored lesion is typical of dermatofibrosarcoma protuberans.

Short fascicles of spindle cells that extend far into septa of the subcutis are typical of dermatofibrosarcoma protuberans.

Cells with oval and wavy nuclei in short fascicles that interweave are characteristic of dermatofibrosarcoma protuberans.


Hashimoto K, Brownstein MH, Jacobiec FA: Dermatofibrosarcoma protuberans. Arch Dermatol. 110:874-885, 1974. 4441109

Taylor HB, Helwig EB: Dermatofibrosarcoma protuberans. Cancer. 15:717-725, 1961.

Search for dermatofibrosarcoma protuberans.