Search Results for: langerhans%5C%5C' cells

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A Clinical Atlas of 101 Common Skin Diseases

Histiocytosis X

A proliferation of abnormal Langerhanscells that may affect internal organs, e.g., the spleen, liver, and bone, sometimes with fatal outcome, as well as the skin, where lesions usually manifest themselves as purpuric papules or ulcers that…

Therapeutic Strategies in Dermatology

Histiocytosis X/Langerhans Cell Histiocytoses: Overview

…ytosis) are a group of disorders most common in childhood due to the accumulation or proliferation of a clonal population of cells bearing the phenotype of a Langerhans cell that has been arrested at an early stage of activation and is functionally…

Therapeutic Strategies in Dermatology

Oral Hairy Leukoplakia: Key Points

…reduced numbers of EBV-specific cytotoxic T cells noted in biopsies of OHL, in addition to the absence or reduced number of Langerhans cells, suggest key immunologic factors associated with viral reactivation in affected lesions. Clinically, OHL…

Histologic Diagnosis of Inflammatory Skin Diseases

Cells That Mediate Inflammation (Inflammatory Cells)

…ocytes express major histocompatibility complex (MHC) class II antigens, molecules essential for interactions among lymphoid cells. Langerhanscells also express CD1a and are S-100 positive. If the antigen is large, phagocytosis by…

Histologic Diagnosis of Inflammatory Skin Diseases

Langerhans’ Cells

…virtue of release from them of neuropeptides, such as calcitonin gene-related peptide, are able to modulate the function of Langerhanscells. In sections stained by hematoxylin and eosin, Langerhanscells are seen to be separated from…

Epidermal multinucleated giant cells are not always a histopathologic clue to a herpes virus infection: multinucleated epithelial giant cells in the epidermis of lesional skin biopsies from patients with acantholytic dermatoses can histologically mimic a herpes virus infection

Epidermal multinucleated giant cells are not always a histopathologic clue to a herpes virus infection: multinucleated epithelial giant cells in the epidermis of lesional skin biopsies from patients with acantholytic dermatoses can histologically mimic a herpes virus infection

…Purpose: To review the histologic differential diagnosis of conditions with epithelial and histiocytic multinucleated giant cells—since multinucleated giant cells in the epidermis are not always pathognomonic of a cutaneous herpes virus…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Langerhans’ Cell Granulomatosis?

…nd eosinophils in varying proportions.” Wakatsuki S, Hirokawa M, Horiguchi H, et al. Hypersegmentation of inflammatory cells in Langerhans cell granulomatosis. Diagn Cytopathol 2000;23:238–41. Search Derm101.com for Langerhans’ cell…

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