Search Results for: fibrin

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Histologic Diagnosis of Inflammatory Skin Diseases

Leprosy

…nt of nerve fascicles by granulomas (a consequence of neurotropism by leprae bacilli), and absence of caseous necrosis or of fibrin in the center of granulomas. In brief, a histopathologist may offer a diagnosis presumptive of tuberculoid leprosy,…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Perivasculitis?

…thing as perivasculitis. Vasculitis of small vessels in the skin, when developed fully, is characterized by the presence of fibrin in the wall of vessels, thrombi in the lumen of vessels, or both together in the context of an infiltrate of…

Histologic Diagnosis of Inflammatory Skin Diseases

Mucha-Habermann disease

…es acuta. Misconceptions about Mucha-Habermann disease abound. For one, Mucha-Habermann disease is not a vasculitis, because fibrin is not present in the wall of venules and thrombi are not found within the lumen of them. The presence rarely of…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…and shape 8. No abnormal endothelial cells 8. Abnormal endothelial cells sometimes protrude into the lumen of vessels 9. No fibrin around venules in the upper part of the dermis 9. Fibrin sometimes present around venules in the upper part of the…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…redominate 6. Multinucleate histiocytes common 6. No multinucleate histiocytes as a rule 7. Mucin, degenerated collagen, and fibrin in the center of palisades 7. No mucin, degenerated collagen, or fibrin in the center of palisades 8. Remnants of…

Histologic Diagnosis of Inflammatory Skin Diseases

Pernio

…Edema of variable extent, little to marked, in the papillary dermis Lymphocytes sprinkled along the dermoepidermal junction Fibrin sometimes in the wall of dermal venules and thrombi episodically in the lumen of them Mucin often increased in the…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Pernio, Perniosis, Lupus Pernio, Chilblain, and Chilblain Lupus?

…s, edema that varies from little to marked in the papillary dermis, lymphocytes sprinkled along the dermoepidermal junction, fibrin sometimes in the wall of a few dermal venules, and thrombi episodically in the lumen of those vessels. Patchy…

Histologic Diagnosis of Inflammatory Skin Diseases

Lupus erythematosus

…me, which also exhibit neutrophils and nuclear “dust” of neutrophils in perivascular and interstitial locale. If fibrin is present in the wall of venules, the diagnosis is leukocytoclastic vasculitis, not lupus erythematosus or…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…f the persistent pigmented purpuric dermatitides, like the others, is a dermatitis and not a vasculitis. Note the absence of fibrin from the wall of vessels and of thrombi from the lumen of them. 10.78.5A: Perivascular dermatitis, interface,…

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