Search Results for: itch-scratch sequence

Histologic Diagnosis of Inflammatory Skin Diseases

Lupus erythematosus

…o, it now will be for lesions of it histopathologic, after which criteria for diagnosis will be set forth telegraphically in sequence chronological. A “butterfly blush” is characterized histopathologically by a sparse infiltrate of…

Differential Diagnosis in Dermatopathology

Discussions

…ess to become a papule and even a nodule and tumor. The same may be said for macules of melanoma on every site anatomic. The sequence histopathologic of changes in “lentigo maligna”, as in melanoma in situ on all anatomic sites, begins…

Histologic Diagnosis of Inflammatory Skin Diseases

Factitious dermatitis and panniculitis

…of foreign body granulomatous inflammation. Pentazocine panniculitis is manifested as sclerodermoid plaques consequent to a sequence of thrombosis, granulomatous inflammation, and pronounced fibrosis in the dermis and subcutaneous fat. Povidone…

Differential Diagnosis in Dermatopathology

Discussions

…nant (“dermatofibroma”). Later still, sclerosis may prevail (“subepidermal nodular sclerosis”). This sequence of changes is manifested clinically as a reddish papule when there is marked vascularity; a purplish papule when…

Differential Diagnosis in Dermatopathology

Atrophic lichen planus vs. Atrophic discoid lupus erythematosus

Psoriasis is a chronic, immune-mediated polygenic skin disorder affecting approximately 2% of the population. The pathogenesis of psoriasis features an interplay between adaptive and innate immunity centered on interleukin 23 and T-helper 17 cells…

Differential Diagnosis in Dermatopathology

Dermatofibroma vs. Desmoplastic Spitz’s nevus

Psoriasis is a chronic, immune-mediated polygenic skin disorder affecting approximately 2% of the population. The pathogenesis of psoriasis features an interplay between adaptive and innate immunity centered on interleukin 23 and T-helper 17 cells…

Histologic Diagnosis of Inflammatory Skin Diseases

Rosacea

…of infundibular cysts that rupture with subsequent suppuration, granulomatous inflammation, and extensive fibrosis, in that sequence, and of what seems to be proliferation of sebocytes in lobules positioned outside the zones of fibroplasia. It is…

Histologic Diagnosis of Inflammatory Skin Diseases

Pemphigus vulgaris

…l, and vaginal. Mucous membranes are not caught up in the process of pemphigus foliaceus or Hailey-Hailey disease. The usual sequence in pemphigus vulgaris is development of blisters that seem to arise from normal skin, but, as has been mentioned,…