Search Results for: sebocyte-like melanocyte

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Epidemic of Melanoma?

…f evidence that a virus or any other agent is responsible for its development. It makes no sense for a malignant neoplasm of melanocytes of noninfectious cause to suddenly assume proportions epidemic. It makes good sense, however, to explain that…

Nail matrix melanoma: consecutive cases in a general practice

Nail matrix melanoma: consecutive cases in a general practice

…Figure 3 stained with pan-melanoma immunoperoxidase stain shows prominent dendrites with focally confluent plump junctional melanocytes (black arrows) and a Pagetoid melanocyte (red arrow). [Copyright: ©2012 Rosendahl et al.] The patient was…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Precursor Lesions of Melanoma?

…iginous melanocytic proliferation” is a vague description, one that is applicable equally to a benign proliferation of melanocytes (labial lentigo) and a malignant one (melanoma in situ). Neither labial lentigo nor melanoma in situ is a…

Spitz/Reed nevi: a review of clinical-dermatoscopic and histological correlation

Spitz/Reed nevi: a review of clinical-dermatoscopic and histological correlation

…ely spindle-cell nevus, Reed nevus may display a mixed pattern with epithelioid and spindle cells. In classical Spitz nevus, melanocytes are characteristically epithelioid but often also spindle-shaped [3]. Spitz/Reed nevi with atypia include a…

Nodular melanoma: five consecutive cases in a general practice with polarized and non-polarized dermatoscopy and dermatopathology

Nodular melanoma: five consecutive cases in a general practice with polarized and non-polarized dermatoscopy and dermatopathology

…ertical collagen bands, none of these are seen in the dermatopathologic images although abundant collagen surrounds nests of melanocytes (C and D). On the extreme left side (C and shown at high power in D) an eccrine duct can be seen attenuated by a…

Histologic Diagnosis of Inflammatory Skin Diseases

Vitiligo

…ion decreased markedly in number Melanin in the epidermis decreased in amount Late No infiltrate of lymphocytes No epidermal melanocytes No melanin in the epidermis Correlation clinicopathologic Loss of melanocytes leads to an absence of melanin…

Differential Diagnosis in Dermatopathology

Dermatofibroma vs. Desmoplastic Spitz’s nevus

Papules, nodules, and tumors that, on gross examination, are usually skin colored and, on histopathologic examination, consist of an epithelium-lined sac that contains fluid, cells, or both in the case of true cysts and of cysts that are associated…