Search Results for: mastocytosis

Solitary mastocytoma presenting in an adult: report and literature review of adult-onset solitary cutaneous mastocytoma with recommendations for evaluation and treatment

Solitary mastocytoma presenting in an adult: report and literature review of adult-onset solitary cutaneous mastocytoma with recommendations for evaluation and treatment

…. Discussion Mastocytosis, a disease in which there is an accumulation of mast cells in tissues, has two variants: cutaneous mastocytosis and systemic mastocytosis [1-5]. Cutaneous mastocytosis occurs when the mast cell proliferation is limited to…

Histologic Diagnosis of Inflammatory Skin Diseases

Urticaria pigmentosa

…ogical diagnosis. Histol Histopathol 1997;12(4):1081-89. Kurosawa M, Amano H, Kanbe N, et al. Heterogeneity of mast cells in mastocytosis and inhibitory effect of ketotifen and ranitidine on indolent systemic mastocytosis. J Allergy Clin Immunol…

Coexistence of urticaria pigmentosa and thalassemia minor in a young adult

Coexistence of urticaria pigmentosa and thalassemia minor in a young adult

…IT D816V mutation, CD2 and CD25 expression of the bone marrow or affected tissue may be helpful in the diagnosis of systemic mastocytosis in adults [4]. Furthermore, Proelss et al suggest that elevated levels of tryptase in the bone marrow may be a…

Histologic Diagnosis of Inflammatory Skin Diseases

Errors and Reasons

…and telangiectasia macularis eruptiva perstans are different names for different diseases. Reason: Urticaria pigmentosa and mastocytosis are synonyms, referring as they do to diseases of mast cells in general, that is, macular, papular, nodular,…

Billings SD, Cotton J. Inflammatory Dermatopathology. A Pathologist’s Survival Guide. New York: Springer Science + Business Media LLC, 2011

Billings SD, Cotton J. Inflammatory Dermatopathology. A Pathologist’s Survival Guide. New York: Springer Science + Business Media LLC, 2011

…riasiform and lichenoid dermatitis, but there are others, like patch stage Kaposi’s disease, metastatic breast cancer, mastocytosis, B-cell lymphoma, etc., which can mimic interstitial or perivascular dermatitis respectively. I have another…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…of the papillary dermis, the uneven acanthosis, and the huge scale-crust. At higher magnification, however, the diagnosis of mastocytosis becomes evident; mast cells are predominant. The presence of eosinophils is attributable to trauma to the mast…