Search Results for: metastatic squamous-cell carcinoma

The dermatologist’s stethoscope-traditional and new applications of dermoscopy

The dermatologist’s stethoscope-traditional and new applications of dermoscopy

…basal cell carcinoma showing loosely arranged gray globules and focused branching, arborizing vessels. (C) Invasive squamous cell carcinoma showing a white-pink background intermingled with white circles (targetoid appearing follicular openings…

Confusion—specimen mix-up in dermatopathology and measures to prevent and detect it

Confusion—specimen mix-up in dermatopathology and measures to prevent and detect it

…egression of a neoplasm following biopsy of it is a common phenomenon not only in basal-cell carcinoma, but also in squamouscell carcinomas and melanocytic neoplasms [13-15]. Therefore, failure to find remnants of a biopsy-proven neoplasm, coupled…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Halo Phenomenon?

…immune response to melanoma. Although no direct demonstration of melanocyte killing has been observed by the immune effector cells found within the halo, the abundance of antigen-presenting cells in the regressing nevus and the presence of T…

Time to reconsider Spitzoid neoplasms?

Time to reconsider Spitzoid neoplasms?

…bstract” target=”_blank”>PubMed 32. Smith KJ, Barrett TL, Skelton HG III, Lupton GP, Graham JH. Spindle cell and epithelioid cell nevi with atypia and metastasis (malignant Spitz nevus). Am J Surg Pathol 1989; 13(11):931-9….

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Blue Nevus?

…s of DPN. DPN continued shares some clinical and histologic features with those of blue nevus (BN), cellular BN, and spindle cell and epithelioid cell nevus (SEN). However, when a large number of cases of DPN are examined, they are remarkably…

Ocular Inflammation

Ocular Inflammation

…ssue of epibulbar conjunctiva by immunofluorescence and immunohistochemistry; their results showed an increase of nearly all cell types in the conjunctiva of patients with rosacea, but especially of T-helper cells.[17] They concluded that…

Extensive regression in pigmented skin lesions: a dangerous confounding feature

Extensive regression in pigmented skin lesions: a dangerous confounding feature

…entation The fully regressed melanoma in Figure 1 was found on the arm of a 50-year-old man, who was recently diagnosed with metastatic melanoma of the ipsilateral axillary lymph nodes (Figure 1A). Dermoscopic examination revealed a diffuse…

Hypopigmented atypical Spitzoid neoplasms (atypical Spitz nevi, atypical Spitz tumors, Spitzoid melanoma): a clinicopathological update

Hypopigmented atypical Spitzoid neoplasms (atypical Spitz nevi, atypical Spitz tumors, Spitzoid melanoma): a clinicopathological update

…opathologic study of 27 cases. Cancer 1960;13:612-25. 5. Smith KJ, Barrett TL, Skelton HG 3rd, Lupton GP, Graham JH. Spindle cell and epithelioid cell nevi with atypia and metastasis (malignant Spitz nevus). Am J Surg Pathol 1989;13:931-39. 6….

Differential Diagnosis in Dermatopathology

Seborrheic keratosis, acanthotic type vs. Eccrine poroma

Mammary Paget’s disease is an apocrine carcinoma that begins in mammary glands and extends along lactiferous ducts to the epidermis where it is seen clinically as a scaly, crusted, or eroded plaque on the nipple or areola of women mostly, and…