Search Results for: clark-like nevus

Histologic Diagnosis of Inflammatory Skin Diseases

Sebaceous Units

…d isthmus and descending for a short distance parallel to the follicle. What in sections of tissue oriented vertically looks like a cloak composed of cords of undifferentiated cells is seen in sections oriented horizontally to be a skirt that…

Differential Diagnosis in Dermatopathology

Discussions

…pparently banal solar lentigo calls forth a lichenoid infiltrate of lymphocytes and, in the process, becomes a lichen planus-like keratosis, which is a forerunner to regression entirely of the original benign neoplasm of keratocytes, remains an…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Subcorneal Pustular Dermatosis?

…neal pustular dermatosis, spongiform pustules occur only in pustular psoriasis.” Cohen LM, Karpskopicki D, Harrist TJ, Clark WH JR. Noninfectious vesiculobullous and vesiculopustular diseases. In: Elder D, ed. Lever’s Histopathology of…

Gajewski TF, Hodi FS. Targeted Therapeutics in Melanoma. New York: Springer, 2012

Gajewski TF, Hodi FS. Targeted Therapeutics in Melanoma. New York: Springer, 2012

…re has been difficulty in finding correlation with the model of so-called melanoma “progression” as advocated by Clark et al (1984) [1] to the genomics of melanoma. Kashini-Sabet, in chapter 2 (Melanoma Genomics), rightly states that…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Epidemic of Melanoma?

…of an epidemic. West J Med 1988;149:43-46. “The epidemic of melanoma poses problems for several constituencies.” Clark WH, Elder DE, Guerry IV D. Dysplastic nevi and malignant melanoma. In: Farmer ER, Hood AF, eds. pathology of the skin….

Histologic Diagnosis of Inflammatory Skin Diseases

Lupus erythematosus

…e affiliated with a lichenoid infiltrate of lymphocytes, thereby requiring differentiation from lichen planus, lichen planus-like dermatitides, and lichen planus-like keratosis. The predilection of lymphocytes for epithelial structures of adnexa, a…

A case of a superficial spreading melanoma in situ diagnosed via digital dermoscopic monitoring with high dynamic range conversion

A case of a superficial spreading melanoma in situ diagnosed via digital dermoscopic monitoring with high dynamic range conversion

…and structure, but was darker in the center and paler at the periphery. Therefore, the macule was tentatively diagnosed as a Clark nevus, and a 6-month follow-up was recommended. When the patient presented 7 months later, the lesion had enlarged to…