Search Results for: basement%20membrane

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Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…ulation. BASAL LAMINA: See LAMINA DENSA. BASEMENT MEMBRANE [L. basis (ground) + membrana (skin, pergament)]: The term “basement membrane” derives from observations of findings by conventional microscopy in contrast to “basal…

Histologic Diagnosis of Inflammatory Skin Diseases

Lichen planus

…ing, e.g., in the case of lupus erythematosus, no superficial and deep perivascular infiltrates of lymphocytes, no thickened basement membrane, and no thinned epidermis, and in the case of psoriasis, no psoriasiform acanthosis, no thinned…

Histologic Diagnosis of Inflammatory Skin Diseases

Lupus erythematosus

…d lesions demonstrates granular deposits of one or more immunoglobulins (two concurrently being virtually diagnostic) at the basement membrane zone (in patients with widespread disease, findings identical can be seen in clinically normal skin [a…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Subacute Cutaneous Lupus Erythematosus?

…mination between SCLE and DLE was accomplished in 82%. The specimens from DLE lesions had substantially more hyperkeratosis, basement membrane thickening, follicular plugging, and superficial and deep inflammatory cell infiltrate, while SCLE had…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Paraneoplastic Pemphigus?

…erosions, and an array of histologic features, including (2) epidermal acantholysis and interface changes, (3) epidermal and basement membrane-zone deposition of IgG and complement as seen with direct immunofluorescence, (4) detection of serum…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Inverted Follicular Keratosis, Tricholemmoma, and Desmoplastic Tricholemmoma?

…ut follicular infundibula, basaloid palisading at the periphery of tumor lobules, and development of a thickened, hyalinized basement membrane.” Murphy G. Adnexal tumors. In: Dermatopathology: A Practical Guide to Common Disorders….

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Diabetic Dermopathy?

…re as well as in other small blood vessels and may result in decreased cutaneous blood flow. Reduplication and thickening of basement membranes have been shown in diabetic skin. Veil cells are seen more frequently surrounding cutaneous vessels. It…

Histologic Diagnosis of Inflammatory Skin Diseases

Embryologic Development

…ualized through an electron microscope, consists of a lamina lucida and a lamina densa, and contains molecules common to all basement membranes. At about 12 weeks, the dermoepidermal interface is punctuated at intervals nearly equidistant from one…

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