Search Results for: cleft

Histologic Diagnosis of Inflammatory Skin Diseases

Langerhans’ Cells

…n sections stained by hematoxylin and eosin, Langerhans” cells are seen to be separated from adjacent keratocytes by a cleft, just as melanocytes are separated from keratocytes by a space, a finding that for more than a century caused them to…

Reflectance confocal microscopy of a mammary Paget disease

Reflectance confocal microscopy of a mammary Paget disease

…ave seen on RCM were actually similar to the morphology of dark silhouettes of BCC. However, the lack of typical peritumoral cleft-like spaces and localization of the nests through the epidermal layer were the features opposing this diagnosis. The…

Histologic Diagnosis of Inflammatory Skin Diseases

Hair Follicles

…often appears a marker helpful morphologically to discerning a site crucial to a follicle biologically, namely, artifactual clefts that form between an inner sheath about to cornify and a hair about to do the same. Although the process of…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…hion 2. No wedge-shaped hypergranulosis as a rule; hypergranulosis without a wedge episodic and not in repeatable pattern 3. Cleft between atrophic epidermis and dermis common 3. Cleft between atrophic epidermis and dermis uncommon 4. No thickened…

Histologic Diagnosis of Inflammatory Skin Diseases

Grover’s disease

…mostly cohesive, they may be unassociated with parakeratosis (pemphigus vulgaris type), they may be present above suprabasal clefts in an epidermis characterized by acantholytic cells throughout at least half the thickness of the spinous zone…

Histologic Diagnosis of Inflammatory Skin Diseases

Lichen planus

…umulated at the dermoepidermal junction as a product of the extraordinarily accelerated process that culminates in vesicles. Clefts cannot be seen clinically; blisters can be. Histopathologically, clefts in lichen planus seem to represent a…