…unbearable pruritus: ulcer secondary to excoriation. This lesion of Grover’s disease, typified by a tiny suprabasilar cleft above which are incipient acantholytic cells, must have been maddeningly pruritic because the ulcer covered by crust…

…n sections stained by hematoxylin and eosin, Langerhans” cells are seen to be separated from adjacent keratocytes by a cleft, just as melanocytes are separated from keratocytes by a space, a finding that for more than a century caused them to…

…often appears a marker helpful morphologically to discerning a site crucial to a follicle biologically, namely, artifactual clefts that form between an inner sheath about to cornify and a hair about to do the same. Although the process of…

…umulated at the dermoepidermal junction as a product of the extraordinarily accelerated process that culminates in vesicles. Clefts cannot be seen clinically; blisters can be. Histopathologically, clefts in lichen planus seem to represent a…

…mostly cohesive, they may be unassociated with parakeratosis (pemphigus vulgaris type), they may be present above suprabasal clefts in an epidermis characterized by acantholytic cells throughout at least half the thickness of the spinous zone…