Search Results for: vesicle

Histologic Diagnosis of Inflammatory Skin Diseases

Mucha-Habermann disease

…ma of the papillary dermis and vacuolar alteration along the dermoepidermal junction or of rupture of a tense intraepidermal vesicle. Some vesicles of Mucha-Habermann disease may be wholly intraepidermal, some wholly subepidermal, and some both…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

…gA dermatosis, urticarial stage + Hyphae in the stratum corneum = Dermatophytosis + Collections of eosinophils in spongiotic vesicles = Incontinentia pigmenti + Perivascular and interstitial infiltrate of lymphocytes and eosinophils = Drug eruption,…

Histologic Diagnosis of Inflammatory Skin Diseases

Lichen planus

…ytes. Features typical of a papule of lichen planus are not seen beneath a subepidermal blister of lichen planus because the vesicle is the result of acceleration remarkably of the fundamental process pathologic of lichen planus. The lesion evolves…

Histologic Diagnosis of Inflammatory Skin Diseases

Confusing Terms (to be Avoided Scrupulously)

…or changes seen histopathologically, namely, a small collection of neutrophils within an epithelium or nonepithelium, a tiny vesicle caused by spongiosis, ballooning, or acantholysis, and a little cyst, usually an epidermal (infundibular) one, known…

Differential Diagnosis in Dermatopathology

Discussions

…” that consists clinically of a vesicle atop an urticarial papule or plaque will reveal a large central intraepidermal vesicle with smaller intraepidermal vesicles that taper progressively in size toward the periphery of the lesion, whereas a…

Epidermal multinucleated giant cells are not always a histopathologic clue to a herpes virus infection: multinucleated epithelial giant cells in the epidermis of lesional skin biopsies from patients with acantholytic dermatoses can histologically mimic a herpes virus infection

Epidermal multinucleated giant cells are not always a histopathologic clue to a herpes virus infection: multinucleated epithelial giant cells in the epidermis of lesional skin biopsies from patients with acantholytic dermatoses can histologically mimic a herpes virus infection

…er views of the initial biopsy specimen that showed features consistent with a herpes virus infection. (A) An intraepidermal vesicle with suprabasilar epidermal acantholysis and cleft formation is noted. (B and C) Closer views show neutrophils and…

Differential Diagnosis in Dermatopathology

Urticarial reaction to an arthropod assault vs. Urtica

A blistering inflammatory disease in which acantholysis occurs in the upper part of the spinous zone or granular zone of the epidermis, the result of the process being flaccid blisters that give way to erosions and crusts accompanied by erythema….