Search Results for: vesicle

Histologic Diagnosis of Inflammatory Skin Diseases

Confusing Terms (to be Avoided Scrupulously)

…or changes seen histopathologically, namely, a small collection of neutrophils within an epithelium or nonepithelium, a tiny vesicle caused by spongiosis, ballooning, or acantholysis, and a little cyst, usually an epidermal (infundibular) one, known…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

…gA dermatosis, urticarial stage + Hyphae in the stratum corneum = Dermatophytosis + Collections of eosinophils in spongiotic vesicles = Incontinentia pigmenti + Perivascular and interstitial infiltrate of lymphocytes and eosinophils = Drug eruption,…

Differential Diagnosis in Dermatopathology

Discussions

…” that consists clinically of a vesicle atop an urticarial papule or plaque will reveal a large central intraepidermal vesicle with smaller intraepidermal vesicles that taper progressively in size toward the periphery of the lesion, whereas a…

Epidermal multinucleated giant cells are not always a histopathologic clue to a herpes virus infection: multinucleated epithelial giant cells in the epidermis of lesional skin biopsies from patients with acantholytic dermatoses can histologically mimic a herpes virus infection

Epidermal multinucleated giant cells are not always a histopathologic clue to a herpes virus infection: multinucleated epithelial giant cells in the epidermis of lesional skin biopsies from patients with acantholytic dermatoses can histologically mimic a herpes virus infection

…er views of the initial biopsy specimen that showed features consistent with a herpes virus infection. (A) An intraepidermal vesicle with suprabasilar epidermal acantholysis and cleft formation is noted. (B and C) Closer views show neutrophils and…

Differential Diagnosis in Dermatopathology

Urticarial reaction to an arthropod assault vs. Urtica

An inflammatory process caused by the acarus Sarcoptes scabiei and consisting of papules, papulovesicles, papulopustules, and vesicles, some arranged in linear or curvilinear tracks (burrows). Sometimes nodules are present, especially in the…

Histologic Diagnosis of Inflammatory Skin Diseases

Urticaria

…ate of lymphocytes and eosinophils in conjunction with edema of the papillary dermis and spongiosis (sometimes, a spongiotic vesicle) in the epidermis at the site of the “bite.” Laboratory confirmation None exists. Cause and mechanism…

Histologic Diagnosis of Inflammatory Skin Diseases

Dermoepithelial Interface

…ils; BC, basal cell; D, dermis; HD, hemidesmosome; LD, lamina densa; LL, lamina lucida; PM, plasma membrane; PV, pinocytotic vesicle. (x67,500) (Courtesy of Stephen Katz, M.D.) The plasma membrane of basal keratocytes forms the roof of the…

Histologic Diagnosis of Inflammatory Skin Diseases

Selection of the Method for Surgery

…thologist with sections from which an element critical for diagnosis, i.e., the epidermis, is missing (Fig. 4.1). Tiny tense vesicles, such as those of miliaria crystallina, dyshidrotic dermatitis, and infection by herpesvirus, are an exception to…