Search Results for: vesicle

Eosinophilic dermatosis of hematologic malignancy mimicking varicella zoster infection: report in a woman with chronic lymphocytic leukemia and review of the literature

Eosinophilic dermatosis of hematologic malignancy mimicking varicella zoster infection: report in a woman with chronic lymphocytic leukemia and review of the literature

…id antigen-1 and bullous pemphigoid antigen-2. Figure 3. Microscopic examination of a low magnification view showing a large vesicle (A). Intermediate magnification views (B and C) of the lateral aspects of the vesicle demonstrating that it is…

Histologic Diagnosis of Inflammatory Skin Diseases

Lichen planus

…ytes. Features typical of a papule of lichen planus are not seen beneath a subepidermal blister of lichen planus because the vesicle is the result of acceleration remarkably of the fundamental process pathologic of lichen planus. The lesion evolves…

Epidermal multinucleated giant cells are not always a histopathologic clue to a herpes virus infection: multinucleated epithelial giant cells in the epidermis of lesional skin biopsies from patients with acantholytic dermatoses can histologically mimic a herpes virus infection

Epidermal multinucleated giant cells are not always a histopathologic clue to a herpes virus infection: multinucleated epithelial giant cells in the epidermis of lesional skin biopsies from patients with acantholytic dermatoses can histologically mimic a herpes virus infection

…er views of the initial biopsy specimen that showed features consistent with a herpes virus infection. (A) An intraepidermal vesicle with suprabasilar epidermal acantholysis and cleft formation is noted. (B and C) Closer views show neutrophils and…

Differential Diagnosis in Dermatopathology

Discussions

…” that consists clinically of a vesicle atop an urticarial papule or plaque will reveal a large central intraepidermal vesicle with smaller intraepidermal vesicles that taper progressively in size toward the periphery of the lesion, whereas a…

Histologic Diagnosis of Inflammatory Skin Diseases

Suction blister

Suction blister Presentation stereotypical Individual lesions Vesicles and bullae Findings histopathologic Fully developed Subepidermal blister beneath which dermal papillae are preserved No infiltrate of inflammatory cells Correlation…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ls in the dermis and in vesicles in the epidermis = Bullous pemphigoid, vesicular Both authentic intraepidermal (spongiotic) vesicles and subepidermal vesicles are present. In addition, some intraepidermal vesicles have ruptured to become…

Histologic Diagnosis of Inflammatory Skin Diseases

Fixation of the Specimen

…rilesional” zone should be noneroded, noncrusted, and nonvesicular. With rare exceptions, a biopsy specimen of a frank vesicle is useless for interpretation by direct immunofluorescence. In contrast, a biopsy performed for direct…