Search Results for: clear-cell variant of squamous-cell carcinoma

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Cytophagic Panniculitis?

…culitis, deemed it to be a disease that clinically was confined mostly to the skin; cytopathologically, the neoplastic mononuclear cells exhibited little or no nuclear atypia; and biologically, the disease was benign. Winkelmann called the process…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Capillaritis?

…affect capillaries. Small-vessel vasculitides, when developed fully, are characterized by (1) an infiltrate of inflammatory cells and (2) either fibrin in the wall of vessels or thrombi in the lumen of them, or both of those findings together. The…

Histologic Diagnosis of Inflammatory Skin Diseases

Junctional epidermolysis bullosa

…rocytes. Differential diagnosis histopathologic Other cell-poor subepidermal blistering diseases, such as a suction blister, cell-poor pemphigoid, and one expression of acquired epidermolysis bullosa; all of these “cell poor” blistering…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Ichthyoses?

…ts of a clinical spectrum of disorders; generalized forms may be bullous, and localized forms may resemble linear nevi. Intracellular and intercellular edema gives the epidermis a characteristic reticular pattern in histological sections….

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Lymphocytic Infiltration of Jessner?

…pression of discoid lupus erythematosus when the reticular dermis houses formidable mucin, but neither eosinophils or plasma cells. In our view, lymphocytic infiltration of Jessner and Kanof simply is tumid lupus erythematosus. “Although many…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Malignant Spitz Nevus?

…ns of melanocytes. Every “metastasizing Spitz nevus” is a melanoma misdiagnosed as a Spitz nevus. “Spindle cell and epithelioid cell nevi with atypia and metastasis (malignant Spitz nevus) . . . At the Armed Forces Institute of…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…pemphigus foliaceus, pemphigus erythematosus, and fogo selvagem, and from staphylococcal scalded-skin syndrome. Acantholytic cells can be seen atop the base of the blister, to wit, the uppermost part of the spinous zone. If bacteria are demonstrated…

Histologic Diagnosis of Inflammatory Skin Diseases

Grover’s disease

…usually by smooth or only slightly scaly and/or crusted erythematous papules that result from discrete foci of acantholytic cells in the epidermis and a superficial infiltrate of inflammatory cells. The papillary dermis may be edematous to some…