Search Results for: clear-cell variant of squamous-cell carcinoma

Differential Diagnosis in Dermatopathology

Discussions

…isualizable; hardly ever are melanophages noted in lichenoid purpura. The lichenoid purpura of Gougerot-Blum is one of three variants histopathologic of persistent purpuric dermatitides, a group of idiopathic, usually asymptomatic, conditions that…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Capillaritis?

…affect capillaries. Small-vessel vasculitides, when developed fully, are characterized by (1) an infiltrate of inflammatory cells and (2) either fibrin in the wall of vessels or thrombi in the lumen of them, or both of those findings together. The…

Histologic Diagnosis of Inflammatory Skin Diseases

Junctional epidermolysis bullosa

…rocytes. Differential diagnosis histopathologic Other cell-poor subepidermal blistering diseases, such as a suction blister, cell-poor pemphigoid, and one expression of acquired epidermolysis bullosa; all of these “cell poor” blistering…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Cytophagic Panniculitis?

…culitis, deemed it to be a disease that clinically was confined mostly to the skin; cytopathologically, the neoplastic mononuclear cells exhibited little or no nuclear atypia; and biologically, the disease was benign. Winkelmann called the process…

Histologic Diagnosis of Inflammatory Skin Diseases

Erythema nodosum leprosum

…of neutrophils and histiocytes in the dermis Fully developed All the findings in early lesions with the addition of a mixed-cell infiltrate of neutrophils, lymphocytes, plasma cells, and histiocytes in fat lobules Late Extensive fibroplasia in the…

Histologic Diagnosis of Inflammatory Skin Diseases

Miescher’s granuloma of the face

…liography Bibliography for Miescher’s granuloma of the face Hanke CW, Bailin PL, Roenigk HH. Annular elastolytic giant cell granuloma. J Am Acad Dermatol 1979;1:413–21. Leiker DL, Kok SH, Spaas JJ. Granuloma multiforme. A new disease…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…pemphigus foliaceus, pemphigus erythematosus, and fogo selvagem, and from staphylococcal scalded-skin syndrome. Acantholytic cells can be seen atop the base of the blister, to wit, the uppermost part of the spinous zone. If bacteria are demonstrated…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Necrotizing Vasculitis?

…d synonymously for leukocytoclastic vasculitis. In that vasculitic process, venules themselves are not necrotic. Only living cells can become necrotic and endothelial cells of those venules show no signs of necrosis; they, themselves, do not seem to…

Histologic Diagnosis of Inflammatory Skin Diseases

Leprosy

…tis of small blood vessels is responsible for ulceration of lesions in states deemed to be reactional. The presence of mononuclear cells, particularly histiocytes, in nerve fascicles damages those structures, with resultant alterations in sensation….

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Malignant Spitz Nevus?

…ns of melanocytes. Every “metastasizing Spitz nevus” is a melanoma misdiagnosed as a Spitz nevus. “Spindle cell and epithelioid cell nevi with atypia and metastasis (malignant Spitz nevus) . . . At the Armed Forces Institute of…