Search Results for: atrophy

Hyperkeratotic necrobiosis lipoidica

Hyperkeratotic necrobiosis lipoidica

…x 9 cm. Interestingly, a 5.5 x 4.5 cm plaque on the right anterior lower leg exhibited central hyperkeratosis as opposed to atrophy (Figure 2). A punch biopsy of the atrophic plaque on the left forearm was performed, which revealed granulomatous…

Histologic Diagnosis of Inflammatory Skin Diseases

Mycosis fungoides

…ble from the erythroderma of Sézary’s syndrome. Findings histopathologic “Early” patch (devoid of signs of atrophy clinically) Superficial perivascular and variably interstitial infiltrate of lymphocytes Subtle patchy lichenoid…

Histologic Diagnosis of Inflammatory Skin Diseases

Lipodystrophy

…scles may appear to be hypertrophic and veins may seem to be prominent. Differential diagnosis histopathologic Localized fat atrophy secondary to local injections of corticosteroid or insulin is typified by decrease in the size of adipocytes that…

Histologic Diagnosis of Inflammatory Skin Diseases

Lichen planus

…rete ridges as a consequence of the effects of products of lymphocytes, the papillary dermis being somewhat fibrotic and the atrophy being accounted for by the loss of tissue. Lichen planopilaris begins as punctate macules equidistant from one…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Atrophie Blanche?

…r Dermatol Syphilol 1929;36:867–68. “Although previously considered to be due to a vasculitis, atrophie blanche (white atrophy) is best regarded as a manifestation of a vasculopathy in which occlusion of small dermal vessels by fibrin thrombi…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…papillae, followed by loss of epidermal rete ridges, a combination that eventuates in the appearance clinical of superficial atrophy. 10.9.3A: Perivascular and interstitial dermatitis + 10.9.3B: Lymphocytes and plasma cells = Acrodermatitis chronica…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Subacute Cutaneous Lupus Erythematosus?

…mbrane thickening, follicular plugging, and superficial and deep inflammatory cell infiltrate, while SCLE had more epidermal atrophy. The histopathologic differences between SCLE and DLE further support the concept that SCLE is distinct from DLE and…

Histologic Diagnosis of Inflammatory Skin Diseases

Scar

…rophic epidermolysis bullosa, and conventional scars that follow surgical incisions Atrophic scars, such as those of macular atrophy in acne vulgaris, and vaccination scars Differential diagnosis clinical Dermatofibroma is a distinctive type of…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Pseudopelade?

…of Brocq. Dermatologica 1986; 172: 18-26.) Clinical criteria Irregularly defined and confluent patches of alopecia Moderate atrophy (late stage) Mild perifollicular erythema (early stage) Female: male ratio = 3:1 Long course (more than 2 years)…