Search Results for: atrophy

Histologic Diagnosis of Inflammatory Skin Diseases

Errors and Reasons

atrophy as that condition presents itself in the skin clinically, loss of collagen also is contributory; “superficial atrophy” results largely from loss of collagen in dermal papillae, and “mid atrophy” (anetoderma) from…

Differential Diagnosis in Dermatopathology

Discussions

…a late one. Furthermore, in an early lesion, there is no fibrosis in the upper part of the dermis and no signs clinically of atrophy clinically. Atrophy in lichen planus and in discoid lupus erythematosus is of the superficial type characterized…

Differential Diagnosis in Dermatopathology

Atrophic lichen planus vs. Atrophic discoid lupus erythematosus

A disease of infundibulosebaceous units, especially infundibula, that may manifest itself solely as noninflammatory lesions, i.e., comedones and intact cysts, or as inflammatory lesions, i.e., papules, nodules, and pustules. The process may resolve…

Linear atrophoderma of Moulin: a case report and review of the literature

Linear atrophoderma of Moulin: a case report and review of the literature

…stinct pigment incontinence, no inflammation or alteration of connective tissue texture, and the clinical impression of skin atrophy was attributed to atrophy of the subcutaneous tissue [1]. Up to now there have been 30 reported cases of linear…

Histologic Diagnosis of Inflammatory Skin Diseases

Mycosis fungoides

…ble from the erythroderma of Sézary’s syndrome. Findings histopathologic “Early” patch (devoid of signs of atrophy clinically) Superficial perivascular and variably interstitial infiltrate of lymphocytes Subtle patchy lichenoid…

Hyperkeratotic necrobiosis lipoidica

Hyperkeratotic necrobiosis lipoidica

…x 9 cm. Interestingly, a 5.5 x 4.5 cm plaque on the right anterior lower leg exhibited central hyperkeratosis as opposed to atrophy (Figure 2). A punch biopsy of the atrophic plaque on the left forearm was performed, which revealed granulomatous…

Histologic Diagnosis of Inflammatory Skin Diseases

Lipodystrophy

…scles may appear to be hypertrophic and veins may seem to be prominent. Differential diagnosis histopathologic Localized fat atrophy secondary to local injections of corticosteroid or insulin is typified by decrease in the size of adipocytes that…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Atrophie Blanche?

…r Dermatol Syphilol 1929;36:867–68. “Although previously considered to be due to a vasculitis, atrophie blanche (white atrophy) is best regarded as a manifestation of a vasculopathy in which occlusion of small dermal vessels by fibrin thrombi…

Histologic Diagnosis of Inflammatory Skin Diseases

Lichen planus

…rete ridges as a consequence of the effects of products of lymphocytes, the papillary dermis being somewhat fibrotic and the atrophy being accounted for by the loss of tissue. Lichen planopilaris begins as punctate macules equidistant from one…