Search Results for: ballooning

Differential Diagnosis in Dermatopathology

Erythema multiforme vs. Graft-versus-host disease, acute phase

Circular orange-red-blue macule(s) or patch(es) that often becomes a papule(s) or plaque(s) and vesiculates, healing with hyperpigmentation, and that occurs repeatedly at the very same cutaneous and/or mucous membrane site(s), especially the…

Histologic Diagnosis of Inflammatory Skin Diseases

Drug eruptions

…erivascular dermatitis, to wit, perivascular only; perivascular and interstitial; interface, vacuolar, interface, lichenoid; ballooning; spongiotic, and psoriasiform. Of these, interface dermatitis is the most common, and psoriasiform dermatitis is…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…t infiltrate of neutrophils mostly + 10.11.4C + 10.11.4D = Burn The blister shown began in the epidermis as a consequence of ballooning that led to epidermal necrosis; on rupture, the intraepidermal blister became subepidermal, too. Neutrophils are…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…eads to intraepidermal spongiotic vesicles 3. Slight spongiosis early; no spongiotic vesicles 4. Slight ballooning 4. Marked ballooning leads to intraepidermal ballooning vesicles 5. No necrotic keratocytes 5. Necrotic keratocytes range from…

Histologic Diagnosis of Inflammatory Skin Diseases

Arthropod assaults

…being tense blisters. Bullae are a consequence of many large vesicles that developed secondary to spongiosis and, sometimes, ballooning. Contributing to some blisters brought into being by the “bite” of an insect is subepidermal…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…dermatitis, interface, vacuolar + 10.107.2B: An infiltrate of lymphocytes, neutrophils, and eosinophils, slight spongiosis, ballooning, and individual necrotic keratocytes beneath parakeratosis = Toxic shock syndrome The constellation of findings…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…: Vesicular dermatitis, intraepidermal, spongiotic mostly, but also ballooned + 10.2.11B: Necrosis of keratocytes in foci of ballooning = Dyshidrotic dermatitis As a rule, a blister comes into being in dyshidrotic dermatitis, just as it does in…

Differential Diagnosis in Dermatopathology

Pityriasis lichenoides acuta vs. Pityriasis lichenoides chronica

Circular orange-red-blue macule(s) or patch(es) that often becomes a papule(s) or plaque(s) and vesiculates, healing with hyperpigmentation, and that occurs repeatedly at the very same cutaneous and/or mucous membrane site(s), especially the…

Histologic Diagnosis of Inflammatory Skin Diseases

Septic vasculitis

…the subcutaneous fat Edema of the papillary dermis, sometimes so extensive that a subepidermal blister forms Spongiosis and ballooning possibly leading to formation of intraepidermal blisters; reticular alteration sometimes striking Necrosis of…