Search Results for: drug eruptions

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Therapeutic Strategies in Dermatology

Sarcoidosis: Treatment

…on for patients with widespread skin disease, particularly with recalcitrant facial lesions. Given the teratogenicity of the drug, patients and providers must be registered in the REMS program* to use thalidomide. Patients with the most severe…

Therapeutic Strategies in Dermatology

Sarcoidosis: Key Points

…ore widespread skin disease, or cutaneous disease which fails to respond to topical therapy, antimalarials are generally the drug of choice. Most patients will be treated with hydroxychloroquine 400 mg daily (adhering to an ideal body weight dose…

Therapeutic Strategies in Dermatology

Gonorrhea / Gonococcemia: Key Points

…observed. N. gonorrhoeae has shown a concerning ability to acquire and develop antimicrobial resistance, with emerging multidrug resistant strains representing a public health crisis, particularly with the development of ceftriaxone resistance….

Therapeutic Strategies in Dermatology

Dermatophyte Infections: Initial Evaluation: Tinea Unguium / Onychomycosis

…ort of the nail folds or nail bed), history of recurrent cellulitis, diabetes or immunosuppression (though comorbidities and drugdrug interaction concerns may limit or contraindicate systemic therapy in some cases). Of note, treatment of fingernail…

Histologic Diagnosis of Inflammatory Skin Diseases

Drug eruptions

…Immunosuppressed patients, among them those infected with the human immunodeficiency virus, are susceptible particularly to drug eruptions. Distribution of lesions Widespread and symmetric, except for fixed drug eruption, which often presents…

Histologic Diagnosis of Inflammatory Skin Diseases

Drug eruptions

…ef among them barbiturates and sulfonamides. It is the only type of drug eruption that can be diagnosed with surety histopathologically, the findings in it being entirely specific, unlike the situation in drug eruptions of all other kinds….

Therapeutic Strategies in Dermatology

Linear IgA Bullous Dermatosis: Introduction

…ially in adults. Clinical manifestations do not usually differ from idiopathic disease. Onset is typically within 2 weeks of drug exposure. Associations Culprit drugs include: Antibiotics: vancomycin* (most common), penicillins, cephalosporins,…

Therapeutic Strategies in Dermatology

Fixed Drug Eruption: Initial Evaluation

…rug cannot always be easily identified, especially when the history is unclear or multiple medications are taken. A detailed drug history including sporadically-taken and over-the-counter medications can help in determining the causative drug….

Therapeutic Strategies in Dermatology

Lichenoid Drug Eruption: Key Points

…onths to years after medication exposure and can take weeks to months to subside after medication withdrawal. Binding of the drug to the epidermis is thought to alter its antigenicity and induce a cytotoxic cellular response mediated by CD8+ T…

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